This content is machine translated Mantle cell lymphoma Recurrence after BTK inhibition – prognostic factors and treatment options Mantle cell lymphoma (MCL) is a rare B-cell non-Hodgkin’s lymphoma with a markedly heterogeneous course. The spectrum ranges from indolent, slowly progressive forms to highly aggressive variants. Diagnosis and treatment...…
View Post 11 min This content is machine translated Myelofibrosis New findings on the role of inflammation in pathogenesis Myelofibrosis is an inflammation-driven systemic disease in which cytokines, fibrosis and clonal evolution are inextricably linked. New data show that the control of inflammation has a decisive influence on the...…
View Post 6 min This content is machine translated Platelet and leukocyte abnormalities Clonal or reactive causes? The range of causes of blood count changes is diverse. A bone marrow puncture should be performed at a low threshold if red flags are present and is carried out,...…
View Post 9 min This content is machine translated B-cell lymphomas Bispecific antibodies – mechanisms, evidence and future role Bispecific antibodies represent an important therapeutic advance in the treatment of aggressive B-cell lymphomas. Through the targeted recruitment of T cells against malignant B cells, they open up new options...…
View Post 33 min This content is machine translated CRC, AML and melanoma in focus Molecular mechanisms of tumor plasticity Tumor plasticity, epigenetic reprogramming and the dynamic tumor microenvironment shape the biology of CRC, AML and melanoma and influence their therapeutic vulnerability. Modern therapeutic approaches combine molecular profiles, TME signatures...… CME-Test
View Post 13 min This content is machine translated Acute myeloid leukemia Treatment decisions between MRD monitoring, transplantation and CAR-T cells As part of the SOHC 2025 (Swiss Oncology & Hematology Congress), Christoph Röllig from Dresden University Hospital gave a presentation on current developments in the diagnosis and treatment of minimal...…
View Post 12 min This content is machine translated Diabetic ketoacidosis Recommendations for action in practice Diabetic ketoacidosis (DKA) is an acutely life-threatening complication of diabetes mellitus that occurs predominantly in type 1 diabetes, but is also increasingly occurring in people with type 2 diabetes. A...… CME-Test
View Post 7 min This content is machine translated Longevity Medicine 2025 From anti-ageing to precision prevention Longevity Medicine in 2025 is less a marketing term than a clinical work program: moving away from fuzzy “anti-aging” promises towards measurable risk, biomarker and intervention logic. Drivers are a...…
View Post 9 min This content is machine translated Myelofibrosis New treatment options for myelofibrosis patients with a high risk of anemia? Myelofibrosis is considered one of the most complex myeloproliferative neoplasms – with high symptom burden, progressive cytopenia and limited treatment options – with anemia in particular presenting a clinical challenge...…
View Post 12 min This content is machine translated Multiple myeloma DREAMM-8: Key study in the development of BCMA therapy up to DREAMM-14 The DREAMM-8 data presented at this year’s ASCO provided robust evidence of the efficacy and tolerability of the BPd combination (belantamab mafodotin, pomalidomide and dexamethasone) for the treatment of recurrent...…
View Post 5 min This content is machine translated Hemophilia A and B Personalized approach and innovative treatment options Severe haemophilia carries a high risk of life-threatening complications if left untreated. In addition to the classic therapeutic principle of substituting the missing coagulation factor, new treatment options have been...…
