This content is machine translated Prurigo nodularis: evidence-based treatment Targeted therapy options on the rise The pathophysiology of prurigo nodularis (PN) is multifactorial and complex, but great progress has recently been made in terms of treatment options. In addition to the monoclonal antibodies dupilumab and...…
View Post 6 min This content is machine translated Chronic urticaria: new treatment alternatives in sight If antihistamines are not sufficient and IgE levels are low Chronic urticaria often leads to a high level of suffering, but new treatment options are on the way – a lot has happened since the publication of the current S3...…
View Post 7 min This content is machine translated Atopic dermatitis as a door opener for an atopic cascade? AD trajectories: Summary of current findings Epidemiologic analyses and longitudinal studies show that the majority of infants affected by AD are symptom-free as adults, but in some, AD persists into adulthood. This is associated with an...…
View Post 7 min This content is machine translated Chronic hand eczema Occupational health aspects and modern therapy management Hand eczema is caused by a complex interaction of genetics, environment and immunological dysregulation. Cumulative exposure to irritants is a major driver of occupational hand eczema. Accordingly, a medical history...…
View Post 4 min This content is machine translated Trichophyton indotineae Terbinafine-resistant dermatophytoses are on the rise in Central Europe Trichophyton indotineae (T. indotineae) often causes persistent, recurrent skin infections and is spreading worldwide. The fact that the number of cases has also increased in Central Europe in recent years...…
View Post 4 min This content is machine translated Lichen sclerosus Interim analysis of a new register So far, 60 patients1 with lichen sclerosus were included in the registry launched in Germany. The mean age of the included patients is 54 years 2. An interim assessment shows...…
View Post 5 min This content is machine translated Severe asthma and CRSwNP Multidisciplinary collaboration between pneumology, allergology and ENT Severe eosinophilic asthma (SEA) and chronic rhinosinusitis with nasal polyps (CRSwNP) are overlapping clinical entities united by a common pathophysiological basis of type 2 inflammation. The frequent co-occurrence of these...…
View Post 5 min This content is machine translated Seborrheic dermatitis in adults Do not underestimate the symptom burden Seborrhoeic eczema is caused by a complex interplay of dysbiosis, impaired skin barrier function and immunological dysregulation. It occurs preferentially in areas rich in sebaceous glands and is associated with...…
View Post 5 min This content is machine translated Moderate to severe atopic dermatitis Established and novel biologics – the therapeutic landscape is in flux Clinically, atopic dermatitis (AD) manifests itself through a polymorphic picture of efflorescences, with pruritus and xerosis in the foreground. In addition to the antibody therapies dupilumab, tralokinumab and lebrikizumab, which...…
View Post 4 min This content is machine translated Case series Mast cell activation syndrome (MCAS) MCAS is now understood as an independent disorder in contrast to systemic or cutaneous mastocytosis. The signs and symptoms can affect the skin, the gastrointestinal tract and the cardiovascular system,...…
View Post 9 min This content is machine translated Irritable Bowel Syndrome “Best practice” recommendations for step-by-step clarification and stage-adapted therapy The diagnosis of irritable bowel syndrome (IBS) is based on the Rome IV criteria for functional gastrointestinal disorders. The main symptoms are abdominal pain and altered bowel habits, but patients...…
