This content is machine translated Xerosis cutis in Older Adults Emollients with humectants such as urea or glycerin: clinical evidence Due to the biophysical properties of their ingredients, emollients restore skin moisture and the skin’s barrier function. For this reason, appropriate topical preparations are used, among other things, to treat...…
View Post 8 min This content is machine translated Atopic Dermatitis in Children and Adults Topically Applied “Small Molecules”: Janus Kinases or PDE-4 as Targets? Intracellular target structures have gained importance as therapeutic targets for small-molecule therapeutics in atopic dermatitis (AD), and topical formulation ensures a localized pharmacological effect, thereby promoting a favorable safety profile...…
View Post 9 min This content is machine translated Atopic Dermatitis: Precisely Targeting Immunological Targets Interleukin blockade or OX40-(L) inhibition? The pathogenesis of atopic dermatitis (AD) involves a complex cascade that occurs at various levels. Immunomodulatory antibody therapies have been developed for the treatment of moderate-to-severe AD; these therapies interfere...…
View Post 8 min This content is machine translated Alopecia areata Should I recommend topical or systemic treatment? For localized and limited hair loss, first-line treatment usually involves the use of corticosteroids, which are administered in topical formulations and/or as intralesional injections. Topical minoxidil is another treatment option...…
View Post 7 min This content is machine translated Acne vulgaris: Topical and Systemic Treatment Options Spotlight on “Hot Topics” The recent reapproval of topical clascoterone in the U.S., the EU, and the U.K. represents a significant expansion of the therapeutic arsenal. Regarding benzoyl peroxide (BPO), the debate over whether...…
View Post 8 min This content is machine translated Chronic Urticaria: Treatment for Patients Unresponsive to Antihistamines In addition to anti-IgE antibodies, the guideline recommends anti-IL-4α antibodies and BTK inhibition The 2026 revised edition of the international urticaria guidelines incorporates the latest findings on pathogenesis and treatment options. Chronic spontaneous urticaria (CSU) encompasses various immunological endotypes with implications for the...…
View Post 8 min This content is machine translated Chronic hand eczema: common, long-lasting, and distressing Non-steroidal anti-inflammatory treatment options are essential for long-term management Chronic hand eczema (CHE) is one of the most persistent inflammatory skin conditions in adults. About one-third of patients suffer from moderate to severe hand eczema. The treatment of CHE...…
View Post 5 min This content is machine translated Case study Discoid Lupus Erythematosus in a 38-Year-Old Woman Discoid lupus erythematosus (DLE) accounts for 50–80% of all cases of chronic cutaneous lupus, making it the most common subtype. The diagnosis is primarily clinical but is supported by histopathology...…
View Post 10 min This content is machine translated Alopecia areata in children, adolescents, and adults New Guideline Classifies the Evidence Base for Topical and Systemic Therapies The severity of alopecia areata has significant implications for counseling and treatment planning; however, to ensure the best possible care, the patient’s age, the individual impact of hair loss, and...…
View Post 7 min This content is machine translated Actinic keratoses Targeted Treatment of Multiple AK Lesions—Balancing Efficacy and Convenience Actinic keratoses occur singly or in confluent patches on sun-exposed areas of the skin. Clinical and/or dermatoscopic diagnosis can be supported by non-invasive diagnostic tools such as confocal microscopy and...…
View Post 3 min This content is machine translated Psoriasis Research: What's in the Pipeline? Highly selective oral TYK inhibitors in Phase III Envudeucitinib and Zasocitinib are oral, allosteric tyrosine kinase 2 (TYK2) inhibitors currently being evaluated in clinical trials for plaque psoriasis. The interim results presented during the Late-Breaking Research sessions at...…
