Targeted Treatment of Multiple AK Lesions—Balancing Efficacy and Convenience

Actinic keratoses occur singly or in confluent patches on sun-exposed areas of the skin. Clinical and/or dermatoscopic diagnosis can be supported by non-invasive diagnostic tools such as confocal microscopy and LC-OCT, which are also used to monitor treatment efficacy [1]. The current European guideline recommends field-directed treatment with topically applied preparations or photodynamic therapy for multiple AK lesions [2]. Various topical active ingredients with different application regimens and mechanisms of action are available.