This content is machine translated Autoimmune Liver Diseases Innovative Treatment Approaches for PBC, PSC, and AIH: What’s New? PPAR agonists as second-line therapy have proven effective in primary biliary cholangitis (PBC) not only in clinical trials but also in real-world settings, as recent research findings show. In primary...…
View Post 8 min This content is machine translated Myelofibrosis Mutations and Molecular Diagnostics in Treatment Decisions Primary myelofibrosis (PMF) is a rare, biologically complex myeloproliferative neoplasm whose course is strongly influenced by molecular, epigenetic, and immunological factors. Advances in genomics, spatial transcriptomics, and targeted therapies have...…
View Post 5 min This content is machine translated Psoriasis in the Age of Precision Medicine Systemic Therapy for Patients with Comorbidities: What Is the Best Choice? Psoriasis is a chronic inflammatory systemic disease often associated with comorbidities, a fact that must be taken into account during treatment. Particular attention should be paid to psoriatic arthritis (PsA),...…
View Post 13 min This content is machine translated The AMALFI study and the limits of digital screening for atrial fibrillation Remote monitoring for atrial fibrillation: lots of detection, little stroke prevention? Atrial fibrillation (AF) is often asymptomatic, increases stroke risk and can be treated with anticoagulation – so the logic of screening seems compelling. New patches, loop recorders and smartwatches promise...…
View Post 4 min This content is machine translated MASH Pharmacotherapies as “Game Changers”—What Are the Upcoming Challenges? Two drug therapy options—semaglutide (s.c.) and resmetirom (oral)—are now approved in the EU and the U.S. for the treatment of MASH. This is a major breakthrough, especially since, for a...…
View Post 13 min This content is machine translated Obesity Treatment Oral GLP-1 Therapies: ATTAIN-1 and OASIS-4—The Next Leap Forward Injectable GLP-1 receptor agonists and the dual GIP/GLP-1 agonist tirzepatide have redefined pharmacological obesity treatment and achieved weight loss in the range of 15 to 20% in clinical trials. Nevertheless,...…
View Post 5 min This content is machine translated Older patients with atopic dermatitis Why the Use of Biologics Is Recommended In light of demographic trends, an increase in the prevalence of atopic dermatitis is also being observed among the elderly population. Tailored treatment plans take into account a wide range...…
View Post 4 min This content is machine translated Disorders of the Gut-Brain Interaction Peppermint-Caraway Oil Supplement Proves Effective in Phase IV Trial In primary care , disorders of the gut-brain axis—also known as functional gastrointestinal disorders—are very common. Herbal remedies, such as a proprietary combination of peppermint oil (Mentha × piperita L.)...…
View Post 5 min This content is machine translated Gepante for Migraines Relief from pain, symptoms, and improved functional ability—both acute and preventive Migraine management goes beyond acute symptom control and may also include preventive strategies for patients with a significant disease burden. Although triptans remain the recommended first-line treatment for acute migraine,...…
View Post 12 min This content is machine translated Why the Finerenon Boom Is Giving Hyperkalemia Treatment New Relevance Potassium binders as enablers of RAASi optimization Renin-angiotensin-aldosterone system (RAAS) inhibitors—including mineralocorticoid receptor antagonists (MRAs)—are among the most effective tools in cardiorenal medicine. However, their benefits are often undermined in everyday clinical practice because fear of hyperkalemia...…
View Post 3 min This content is machine translated Asthma in Adults: Bronchodilation and Anti-Inflammatory Therapy Remodeling can be counteracted through a proactive treatment strategy If certain key, evidence-based principles are followed, remission is now an achievable goal in asthma treatment. First, it is recommended to routinely supplement spirometry with a blood test to measure...…
