This content is machine translated Epilepsy Cannabidiol for refractory epilepsy syndromes The pharmaceutical formulation of high-purity cannabidiol is approved for the treatment of seizures associated with Lennox-Gastaut syndrome, Dravet syndrome and tuberous sclerosis complex. Despite many years of clinical experience, there...…
View Post 3 min This content is machine translated Stomach cancer and Helicobacter pylori A question of income? Despite a declining incidence rate, the total number of cases and deaths from gastric cancer continues to rise worldwide. Infection with Helicobacter pylori is the main risk factor for the...…
View Post 7 min This content is machine translated Prurigo nodularis and AD Effective itch relief through inhibition of the IL-31 signaling pathway The vicious circle of itching and scratching is a central element in both prurigo nodularis (PN) and atopic dermatitis (AD). Interleukin (IL)-31, often referred to as the “itch cytokine”, has...…
View Post 12 min This content is machine translated Palliative care symptom and needs assessment. What screening tools are helpful? In view of the new and mostly well-tolerated therapies, the palliative life and treatment time of oncological patients is increasingly extended. It is a major challenge to identify patients in...… CME-Test
View Post 3 min This content is machine translated Brain atrophy and MS Brain atrophy correlates with disability progression in MS Brain atrophy in MS patients, particularly in the thalamus, correlates strongly with long-term physical disability and cognitive deficits. A long-term analysis of the phase 3 studies RADIANCE/SUNBEAM and the open-label...…
View Post 11 min This content is machine translated Alternative to insulin and GLP1 From the β-cell to the center: the versatile role of amylin Although amylin was discovered decades ago, its importance in everyday clinical practice has long been underestimated. New pharmacological developments are increasingly bringing amylin into the focus of diabetes and obesity...… CME-Test
View Post 4 min This content is machine translated Pulmonary sarcoidosis Prednisone vs. MTX: a draw after 24 weeks Pulmonary sarcoidosis remains a persistent clinical challenge in respiratory medicine. Although glucocorticoids have long been the mainstay of first-line therapy, their side effects often complicate long-term treatment. In recent years,...…
View Post 4 min This content is machine translated Friedreich's ataxia Loss of orientation in the cerebellum Spinocerebellar ataxias represent a large group of rare, progressive neurodegenerative diseases that affect the cerebellum and its connections and predominantly manifest themselves in a cerebellar syndrome. In addition to progressive...…
View Post 6 min This content is machine translated Subtyping as the key to precision medicine Molecular diversity of the PDAC Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive tumors of all. The five-year survival rate is still in the single digits. In recent years, however, there has been...…
View Post 4 min This content is machine translated Multiple sclerosis Vitamin D as an adjuvant in multiple sclerosis: statistical success and clinical limitations Various risk factors are involved in the pathogenesis of multiple sclerosis, with vitamin D deficiency being associated with an increased risk of MS since the 1970s. Disease-modifying therapies aim to...…
View Post 5 min This content is machine translated Artificial intelligence for COPD A new era of personalized treatment Chronic obstructive pulmonary disease (COPD) remains one of the leading causes of morbidity and mortality worldwide. The development of artificial intelligence (AI) has led to new ways of effectively treating...…
