Clinical Presentation, Diagnosis, and Treatment of DSPN

Distal symmetric sensorimotor polyneuropathy (DSPN) is the most common form of diabetic neuropathy. About one-third of all diabetes patients are affected by it. They often develop neuropathic pain, although a significant proportion remain completely symptom-free, at least at times—it is precisely these painless courses that are insidious, because they progress unnoticed toward a loss of sensation.