View Post 10 minute read This content is machine translated Pulmonary arterial hypertension beyond the guideline. IPAH or what else? – IPAH with pulmonary comorbidity RX Cardiology CME continuing education Pneumology Studies Pulmonary hypertension is divided into 5 distinct groups, with group 1 reflecting pulmonary arterial hypertension (PAH). The PH-specific drug therapies approved to date interfere with three different signaling pathways (NO signaling pathway, prostacyclin signaling pathway, and endothelin receptor signaling pathway). Much has happened since the first PAH-specific drug (bosentan) was approved in Europe about 20 years ago. Numerous other agents have been added and have improved the prognosis of PAH patients. CME-Test
View Post 10 minute read This content is machine translated Disease of the subcutaneous adipose tissue Lipedema – a painful fatty tissue disease of the extremities in women RX CME continuing education Dermatology and venereology General Internal Medicine Physical medicine and rehabilitation Studies Surgery Unkategorisiert Lipedema is a painful, disproportionate increase in fat in women; on legs and arms, as well as hips and buttocks. Lipedema has been officially classified as a disease in the ICD catalog for several years. The diagnosis is made on the basis of clinical criteria. Liposuction is currently covered in Switzerland if the pain associated with lipedema does not respond adequately to intensive conservative therapy (compression and manual lymphatic drainage) and a recommendation is made by a trusted physician. In addition to surgical and conservative procedures, dietary changes and exercise intensification are among the other pillars of therapy. CME-Test
View Post 4 minute read This content is machine translated Rare diseases Niemann-Pick disease Education General Internal Medicine Genetics Neurology Pediatrics RX Lysosomal storage diseases are a heterogeneous group of genetic disorders that originate from dysfunction of lysosomal metabolic processes. Niemann-Pick disease is nowadays also referred to as ASMD (“Acid Sphingomeyelinase Deficiency”). Type A and B are classified as sphingolipidoses, while type C belongs to lipid storage diseases. For type A and B, the first enzyme replacement therapy was approved in the EU last year.
View Post 6 minute read This content is machine translated Heart Rate Variability – How accurate are smartwatches? Direct comparison with the gold standard in cardiovascular disease Cardiology Education Prevention and health care RX Studies A recent study investigated the agreement between heart rate variability derived from the photoplethysmographic signal of a commercially available smartwatch and heart rate variability derived from high-resolution electrocardiogram (gold standard) in patients with cardiovascular disease.
View Post 4 minute read This content is machine translated Light skin cancer Prevention and early detection of an underestimated disease Congress Reports Dermatology and venereology Interviews Oncology Prevention and health care RX Studies Light skin cancers are the most common cancers in fair-skinned people. They occur in at least 200 out of every 100,000 people per year.in Germany, especially basal cell carcinoma and cutaneous squamous cell carcinoma. Even if the chances of recovery are very good compared to black skin cancer, light skin cancer should not be underestimated. An interview with Prof. Dr. med. Ralf Gutzmer, Minden (Germany).
View Post 4 minute read This content is machine translated Risk stratification for Barrett's esophagus Pathology test beats human experts Congress Reports Gastroenterology and Hepatology General Internal Medicine Oncology RX Studies Low-grade dysplasia is associated with an increased risk of progression in Barrett’s esophagus, but the diagnosis of LGD is limited by considerable interobserver variability. Several studies have shown that the tissue system pathology test TSP-9 is effective in predicting neoplastic progression in patients with BE. A team of researchers from Amsterdam compared the performance of the TSP-9 test in risk stratification with benchmarks from general practitioners and pathology experts.
View Post 5 minute read This content is machine translated Prurigo nodularis New therapeutic approaches are promising Allergology and clinical immunology Congress Reports Dermatology and venereology RX Studies Recent research findings indicate that Th2-associated immune cells and cytokines play an important role in the pathogenesis of prurigo nodularis (PN). This is the therapeutic target of the two biologics, which are seen as a beacon of hope for severely affected patients in particular. Dupilumab blocks the effect of IL-4 and IL-13 and was recently granted an indication extension for PN by Swissmedic. Nemolizumab, also a biologic, is directed against IL-31 and has already been approved in some other countries for the treatment of PN.
View Post 2 minute read This content is machine translated Distal gastrectomy How safe is 5 centimeters? Congress Reports Gastroenterology and Hepatology General Internal Medicine Oncology RX Studies Surgery Adenocarcinoma of the stomach can be treated surgically under certain conditions by means of distal gastric resection. One factor for this is a necessary proximal safety distance to the tumor of either 5 cm or 8 cm, depending on the tumor histology. However, there has been a lack of data to date for more precise determinations and effects on survival.
View Post 3 minute read This content is machine translated Environmental influences and lung health High air pollution = small baby Congress Reports General Internal Medicine Gynecology Pediatrics Pneumology Prevention and health care RX Studies Women who are exposed to high levels of air pollution give birth to smaller babies. Conversely, women who live in greener areas give birth to larger babies, which could counteract the effects of air pollution. This link is shown by a study that adds to the growing body of evidence of adverse health effects caused by air pollution, particularly in infants and young children.
This content is machine translated Waste volumes in endoscopy Economic and resource-saving approaches Congress Reports Gastroenterology and Hepatology General Internal Medicine Practice Management Prevention and health care RX The healthcare sector accounts for around 5% of nationalCO2 production in Switzerland. Endoscopy is one of the most resource-intensive departments and ranks third in terms of waste production. How this can be counteracted in the future was the subject of a study by scientists in Basel.
1 Lower leg ulceration in geriatric patients. Revascularization options in arterial ulcer – a review.
4 Locally advanced or metastatic urothelial carcinoma Subgroup analyses of the JAVELIN Bladder 100 study – In the context of clinical practice.
Swiss Oncology in Motion Module Urothelial Carcinoma CME continuing education Education Oncology Partner Content RX Urology View Post
Shingles vaccination Prevention of herpes zoster CME continuing education Education General Internal Medicine Infectiology Partner Content Prevention and health care RX Studies
Patient-centered rounds in medicine Aligning care with the patient RX CME continuing education Education General Internal Medicine Prevention and health care Studies View Post
Thyroid Diseases Clarification of thyroid nodules RX CME continuing education Education Endocrinology and Diabetology General Internal Medicine Nuclear Medicine Oncology Radiology View Post
Patient-centered rounds in medicine Aligning care with the patient RX CME continuing education Education General Internal Medicine Prevention and health care Studies View Post
Patient-centered rounds in medicine Aligning care with the patient RX CME continuing education Education General Internal Medicine Prevention and health care Studies View Post
Advanced urothelial carcinoma of the urinary bladder Systemic therapy RX CME continuing education Education Oncology Studies Urology View Post
Palliative Care An increasing challenge for the medical profession RX CME continuing education Education General Internal Medicine Prevention and health care View Post
Asthma therapy The mild bronchial asthma CME continuing education General Internal Medicine ORL Pneumology RX Studies View Post
Swiss Oncology in Motion Module Urothelial Carcinoma CME continuing education Education Oncology Partner Content RX Urology View Post
Shingles vaccination (podcast) Herpes zoster prevention CME continuing education Education General Internal Medicine Infectiology Partner Content RX View Post
Psychotherapy Conflict management with patients from foreign cultures CME continuing education Education General Internal Medicine Psychiatry and psychotherapy RX View Post
View Post This content is machine translated Pulmonary arterial hypertension beyond the guideline. IPAH or what else? – IPAH with pulmonary comorbidity RX Cardiology CME continuing education Pneumology Studies Pulmonary hypertension is divided into 5 distinct groups, with group 1 reflecting pulmonary arterial hypertension (PAH). The PH-specific drug therapies approved to date interfere with three different signaling pathways (NO signaling pathway, prostacyclin signaling pathway, and endothelin receptor signaling pathway). Much has happened since the first PAH-specific drug (bosentan) was approved in Europe about 20 years ago. Numerous other agents have been added and have improved the prognosis of PAH patients. CME-Test
View Post This content is machine translated Disease of the subcutaneous adipose tissue Lipedema – a painful fatty tissue disease of the extremities in women RX CME continuing education Dermatology and venereology General Internal Medicine Physical medicine and rehabilitation Studies Surgery Unkategorisiert Lipedema is a painful, disproportionate increase in fat in women; on legs and arms, as well as hips and buttocks. Lipedema has been officially classified as a disease in the ICD catalog for several years. The diagnosis is made on the basis of clinical criteria. Liposuction is currently covered in Switzerland if the pain associated with lipedema does not respond adequately to intensive conservative therapy (compression and manual lymphatic drainage) and a recommendation is made by a trusted physician. In addition to surgical and conservative procedures, dietary changes and exercise intensification are among the other pillars of therapy. CME-Test
View Post This content is machine translated The ageing lung Cellular ageing and senescence CME continuing education General Internal Medicine Geriatrics Pneumology RX Studies What are the causes that lead to an inadequate response to insults? How does an organ like the lung change with age, making the older population more susceptible to age-related diseases such as COPD, lung cancer and idiopathic pulmonary fibrosis (IPF), leading to lower life expectancy, quality of life and higher care needs? And how far are we in the search for the holy grail that will stop ageing and offer us a suitable treatment option for old age? CME-Test
View Post This content is machine translated Invasive pulmonary aspergillosis Correctly diagnose and treat IPA RX Allergology and clinical immunology CME continuing education General Internal Medicine Infectiology Pneumology Radiology Unkategorisiert Aspergillus species can cause a variety of diseases. Among these, invasive pulmonary aspergillosis (IPA) is the most common opportunistic infection caused by moulds in immunocompromised patients and is characterized by acute invasion of hyphae into human tissue. Accordingly, the final proof of IPA is obtained histologically. The mere detection of Aspergillus on an external surface is not sufficient to make a diagnosis. If the presence of Aspergillus is detected in a sample, the correct classification of the findings will guide further diagnosis and treatment. CME-Test
