Partner Content: Highlights
Current CME continuing education
Pulmonary hypertension is divided into 5 distinct groups, with group 1 reflecting pulmonary arterial hypertension (PAH). The PH-specific drug therapies approved to date interfere with three different signaling pathways (NO signaling pathway, prostacyclin signaling pathway, and endothelin receptor signaling pathway). Much has happened since the first PAH-specific drug (bosentan) was approved in Europe about 20 years ago. Numerous other agents have been added and have improved the prognosis of PAH patients.
Lipedema is a painful, disproportionate increase in fat in women; on legs and arms, as well as hips and buttocks. Lipedema has been officially classified as a disease in the ICD catalog for several years. The diagnosis is made on the basis of clinical criteria. Liposuction is currently covered in Switzerland if the pain associated with lipedema does not respond adequately to intensive conservative therapy (compression and manual lymphatic drainage) and a recommendation is made by a trusted physician. In addition to surgical and conservative procedures, dietary changes and exercise intensification are among the other pillars of therapy.
What are the causes that lead to an inadequate response to insults? How does an organ like the lung change with age, making the older population more susceptible to age-related diseases such as COPD, lung cancer and idiopathic pulmonary fibrosis (IPF), leading to lower life expectancy, quality of life and higher care needs? And how far are we in the search for the holy grail that will stop ageing and offer us a suitable treatment option for old age?
Aspergillus species can cause a variety of diseases. Among these, invasive pulmonary aspergillosis (IPA) is the most common opportunistic infection caused by moulds in immunocompromised patients and is characterized by acute invasion of hyphae into human tissue. Accordingly, the final proof of IPA is obtained histologically. The mere detection of Aspergillus on an external surface is not sufficient to make a diagnosis. If the presence of Aspergillus is detected in a sample, the correct classification of the findings will guide further diagnosis and treatment.