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5920 posts
  • This content is machine translated Gepante for Migraines

Relief from pain, symptoms, and improved functional ability—both acute and preventive

Migraine management goes beyond acute symptom control and may also include preventive strategies for patients with a significant disease burden. Although triptans remain the recommended first-line treatment for acute migraine,...…
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  • 12 min
  • This content is machine translated Why the Finerenon Boom Is Giving Hyperkalemia Treatment New Relevance

Potassium binders as enablers of RAASi optimization

Renin-angiotensin-aldosterone system (RAAS) inhibitors—including mineralocorticoid receptor antagonists (MRAs)—are among the most effective tools in cardiorenal medicine. However, their benefits are often undermined in everyday clinical practice because fear of hyperkalemia...…
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  • 3 min
  • This content is machine translated Asthma in Adults: Bronchodilation and Anti-Inflammatory Therapy

Remodeling can be counteracted through a proactive treatment strategy

If certain key, evidence-based principles are followed, remission is now an achievable goal in asthma treatment. First, it is recommended to routinely supplement spirometry with a blood test to measure...…
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  • 3 min
  • This content is machine translated From symptom to diagnosis

Gynecomastia and Adipomastia

The term ” gynecomastia ” refers to the enlargement of the mammary gland in men, which may be unilateral or bilateral. True gynecomastia, caused by an increase in glandular tissue,...…
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  • 7 min
  • This content is machine translated Plastic surgery and reconstructive microsurgery for DFS

Functional limb preservation between infection control, vascular medicine and resurfacing

Diabetic foot syndrome (DFS) is one of the most serious and functionally significant complications of diabetes, with a high number of functionally relevant amputations. DFS is not to be understood...…
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  • 12 min
  • This content is machine translated SURPASS-CVOT

Tirzepatide versus Dulaglutide in T2D with ASCVD

GLP-1 receptor agonists have established themselves in recent years as a class of drugs with cardiovascular protective effects in type 2 diabetes. For dulaglutide, the 2019 REWIND study showed that...…
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  • 6 min
  • This content is machine translated Secondary prevention after ACS: individually optimized lipid management

Trend towards early combination therapy and new strategies for lowering Lp(a)

Secondary prevention after an acute coronary syndrome (ACS) is crucial for improving quality of life and reducing morbidity and mortality rates. Elevated blood lipid levels such as LDL cholesterol and...…
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  • 27 min
  • This content is machine translated Pediatric Brain Tumors

Psychiatry versus Neuro-Oncology: Diagnostic Pitfalls

Pediatric brain tumors often begin with nonspecific symptoms—some physical, some behavioral—that can be attributed to internal medicine or psychiatric differential diagnoses, thereby presenting typical diagnostic pitfalls. Clinical case examples from...…
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  • 13 min
  • This content is machine translated What the latest studies on the entire EF spectrum mean for clinical practice

Heart Failure – The 2026 Evidence Update

Since the release of the 2021 ESC guidelines and the 2022 AHA/ACC/HFSA guidelines, research on heart failure has reached a remarkable level of intensity. Nonsteroidal mineralocorticoid receptor antagonists and incretin-based...…
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  • 5 min
  • This content is machine translated Acute ischemic stroke

Alteplase and Tenecteplase Are on the Same Level

In acute ischemic stroke (AIS), rapid reperfusion therapy is a clinical priority. Although alteplase has been the standard thrombolytic agent for many years, its short half-life requires administration as a...…
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  • 5 min
  • This content is machine translated CKD in People with Type 2 Diabetes: Evidence-Based, Optimized Treatment

SGLT-2 inhibitors and GLP-1 receptor agonists: significant improvement in renal outcomes

Approximately 30–40% of patients with type 2 diabetes develop chronic kidney disease (CKD) over time. In “landmark” studies such as CREDENCE, DAPA-CKD, EMPA-KIDNEY, and several others, SGLT-2 (sodium-glucose-linked transporter 2)...…
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