This content is machine translated SLE: Early use of biologics? Findings from the “Leeds SLE Inception Cohort” If systemic lupus erythematosus (SLE) cannot be adequately controlled with hydroxychloroquine and cortisone preparations, the use of immunomodulatory or immunosuppressive agents and/or biologics should be considered according to current EULAR…
View Post 4 min This content is machine translated Dermatomyositis Impaired mitochondrial function as a trigger for SI joint upregulation? The autoimmune disease dermatomyositis is one of the collagenoses andis characterized by muscular symptoms and characteristic skin florescences. There are indications that the disease is controlled by type I interferon.…
View Post 4 min This content is machine translated "Small Molecules" at AD Current analyses of the pioneer among the JAK-i The first representative of the Janus kinase (JAK) inhibitor class to be approved for atopic dermatitis was baricitinib. In an extensive study program, this selective and reversible inhibitor of JAK-1…
View Post 6 min This content is machine translated Atopic dermatitis and the skin microbiome How does systemic therapy influence dysbiosis? One aim of the multicenter observational study ProRaD is to gain a better understanding of the mechanisms that influence the course of atopic dermatitis (AD). In a sub-project, researchers used…
View Post 7 min This content is machine translated Biologics for AD Interleukin-13 as a target – new long-term data available Now that the range of systemic therapeutics for atopic dermatitis has been expanded and the two monoclonal antibodies dupilumab and tralokinumab as well as three Janus kinase inhibitors have been…
View Post 4 min This content is machine translated Type 2 diabetes Patient-oriented and far-sighted treatment A personalized treatment strategy has become an important basic principle in diabetes therapy. In addition to taking into account inter-individual differences in patient characteristics, certain clusters in relation to the…
View Post 8 min This content is machine translated Lung cancer An overview of non-small cell lung cancer across all stages The European Lung Cancer Congress is a joint project of major multidisciplinary societies representing thoracic oncology specialists working together to advance science, disseminate education and improve the practice of lung…
View Post 6 min This content is machine translated Eosinophilic esophagitis (EoE) Th2 inflammation plays a central role EoE is now considered a type 2-mediated immune disease that is often associated with atopic diseases such as atopic dermatitis, asthma and food allergies. In addition to acid blockers (PPI)…
View Post 3 min This content is machine translated Pneumooncology Optimal treatment of non-small cell lung cancer The treatment management of non-small cell lung cancer has improved significantly in recent years. Innovative treatment options point the way to personalized therapy with fewer side effects and an improved…
View Post 5 min This content is machine translated Chronic heart failure Recognize early and initiate intervention The incidence and prevalence of chronic heart failure are positively correlated with age, although there are other risk factors such as obesity, diabetes and hypertension. In addition to the treatment…
View Post 4 min This content is machine translated TYK2 inhibition in psoriasis What’s new? The JAK-STAT pathway mediates a variety of proinflammatory responses through Janus kinases (JAK)1-3 andtyrosine kinase-2 (TYK2).Deucravacitinib selectively inhibits TYK2 and was shown to be effective and safe in patients with…
