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General Internal Medicine

1723 posts
  • This content is machine translated Chronic renal failure in type 2 diabetes

Using nephroprotective therapy options and slowing progression

In type 2 diabetics, renal function should be checked at regular intervals. Nowadays, modern treatment approaches are available that can slow down the progression of diabetic nephropathy. If early use…
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  • 14 min
  • This content is machine translated Heart failure

Interventional treatment of the tricuspid valve

Long considered the “forgotten valve,” the tricuspid valve (TC) has gained increasing attention and recognition in recent years. This is due in no small part to the development of new…
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  • 1 min
  • This content is machine translated Acute myeloid leukemia

Therapy – if intensive chemotherapy is not possible

AML predominantly affects older individuals, who are often not suitable for intensive chemotherapy due to their age and pre-existing conditions. Younger patients may also be ineligible for intensive chemotherapy due…
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  • 5 min
  • This content is machine translated Systemic mastocytosis

Pathological mast cell infiltration – a clinical challenge

In patients with highly elevated tryptase levels, KIT mutation analysis from bone marrow is recommended. Especially in adults, a point mutation in codon 816 of the KIT gene can often…
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  • 4 min
  • This content is machine translated Chronic pancreatitis

Exocrine insufficiency is treatable by enzyme replacement therapy

Inflammation-induced connective tissue remodeling of the pancreas leads to progressive loss of exocrine and endocrine gland function. For the treatment of exocrine insufficiency – which usually manifests itself late in…
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  • 9 min
  • This content is machine translated Drug interactions

A brief reminder at a glance

Drug interactions are always a challenge in everyday clinical practice. Some combinations may result in a potentially fatal increase in effect or an undesirable loss of effect. In addition, side…
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  • 9 min
  • This content is machine translated Blood pressure control in renal and cardiac patients

Hypertensive diseases in pregnancy

During pregnancy, progesterone causes a drop in blood pressure. Physiologically, this can be attributed on the one hand to the increase in venous vascular capacity (dilatation of the vascular system…
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  • 3 min
  • This content is machine translated Onychomycosis

New guideline summarizes current consensus recommendations

Fungal nail diseases are frequent diagnoses in dermatological practice. What is recommended in terms of material collection and pathogen detection from microscopy and histology to PCR? For which degree of…
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  • 4 min
  • This content is machine translated From symptom to diagnosis

Abdominal pain – Introduction

Abdominal pain may be due to various pathological changes. Various diagnostic methods are used in the clarification process. Imaging techniques are particularly useful for confirming or excluding suspected diagnoses and…
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  • 4 min
  • This content is machine translated Benign prostatic hyperplasia (BPH)

Sabal and Urtica fixed combination: “Real-world” data convincing

In a retrospective study with data from over 70 000 elderly male patients, the effects of the phytotherapeutic PRO 160/120 withthe 5α-reductase inhibitors finasteride and dutasteride, and with theα1-adrenoceptor antagonists…
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  • 5 min
  • This content is machine translated Systemic lupus erythematosus (SLE)

Anifrolumab: 3-year data confirm long-term clinical benefit

New data from a long-term extension study show that anifrolumab was effective, safe, and tolerable in systemic lupus erythematosus (SLE) even in long-term use over three years [1]. Two post-hoc…

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