This content is machine translated GPP: from molecular principles to targeted therapy Therapeutic rationale for targeted IL-36 receptor inhibition The progress in the diagnosis and treatment of generalized pustular psoriasis (GPP) is remarkable. GPP has developed into a clearly defined, independent, IL-36-mediated autoinflammatory disease. Today, the high chronic disease...…
View Post 4 min This content is machine translated Chronic hand eczema Topical pan-JAK-i vs. systemic retinoid: head-to-head study Alitretinoin is currently the only systemic treatment approved for severe chronic hand eczema when patients do not respond adequately to topical corticosteroids. The topical pan-Janus kinase (JAK) inhibitor delgocitinib is...…
View Post 8 min This content is machine translated Atopic dermatitis From skin barrier disorder to atopic march? An early onset and persistent course of atopic dermatitis are the strongest predictors of atopic march. New diagnostic methods such as electrical impedance spectroscopy and the analysis of biomarkers from...…
View Post 8 min This content is machine translated Pneumococcal conjugate vaccine (PCV) Best possible serotype coverage in the respective age group The disease burden of pneumococcal infections is highest in <5-year-old children and ≥65-year-old adults, as well as in the presence of certain comorbidities and in immunocompromised individuals. In Switzerland, there...…
View Post 5 min This content is machine translated HIV: antiretroviral therapy (ART) Single-tablet regimens support adherence According to recent estimates, there are around 17,500 people living with HIV in Switzerland. HIV infection is still not curable, but modern antiretroviral combination drugs can almost completely suppress the...…
View Post 7 min This content is machine translated Rare pulmonary syndromes Yellow nail and Swyer-James syndrome Yellow nail syndrome (YNS) is a rare disease associated with yellowing of the nails, pulmonary manifestations and lymphoedema. A clinical examination and examination of the fingernails can provide valuable information...… CME-Test
View Post 7 min This content is machine translated Vaccinations against viral respiratory infections Influenza, Covid-19 and RSV – Update 2025 The Swiss Vaccination Plan 2025 recommends passive immunization of infants with a monoclonal antibody or vaccination of pregnant women with a recombinant vaccine against RSV. RSV vaccination should also be...…
View Post 4 min This content is machine translated Acute sinusitis: real-world study on first-line therapy Focusing on a rational therapeutic approach beyond antibiotics A retrospective cohort study published in 2024 analyzed data from patients with acute sinusitis in routine care. On the one hand, it was found that over 70% of patients received...…
View Post 7 min This content is machine translated Rare pulmonary syndromes Yellow nail and Swyer-James syndrome Yellow nail syndrome (YNS) is a rare disease associated with yellowing of the nails, pulmonary manifestations and lymphoedema. A clinical examination and examination of the fingernails can provide valuable information...… CME-Test
View Post 4 min This content is machine translated Pelargonium sidoides Scoping review sheds light on the multifaceted spectrum of effects The widely recognized medicinal plant Pelargonium sidoides belongs to the cranesbill family (Geraniaceae) and is also known as Cape geranium. A review published last December summarizes the diverse therapeutic effects...…
View Post 5 min This content is machine translated Case report: L. pneumophila pneumonia Negative test results – but no alternative diagnoses Pneumonia caused by non-serogroup 1 Legionella pneumophila bacteriais a major diagnostic challenge, even for specialists. American physicians describe the case of a woman in whom the majority of tests were...…
