This content is machine translated Cystic Fibrosis CF emergencies Cystic fibrosis is an autosomal recessive genetic disorder in which a defect in the CFTR gene causes disease. The defective chloride channel causes the disease to manifest in different organs.… CME-Test
View Post 6 min This content is machine translated Gout After acute gout attack: long-term reduction of hyperuricemia. The diagnostic gold standard of a gout attack is the detection of urate crystals in the synovial fluid by polarized light microscopy. Anti-inflammatory and analgesic substances are used for acute…
View Post 3 min This content is machine translated Health Services Research International prospective registry study on pustular psoriasis There are still many unanswered questions regarding the pathophysiology, course and treatment options of pustular psoriasis. Because it is a rare condition, there is a lack of large cohort data…
View Post 6 min This content is machine translated Management of rheumatoid arthritis “Anyone diagnosed with RA today wants to be completely symptom-free.” With the development of conventional, biologic, and targeted disease-modifying antirheumatic drugs, the prognosis for rheumatoid arthritis has improved significantly since the 1990s. However, many patients still do not respond to…
View Post 5 min This content is machine translated Diagnosis and therapy of sarcoidosis Lung disease that also affects the rheumatologist Sarcoidosis most commonly affects the lungs, but extrapulmonary manifestations also occur. Isolated involvement of a single organ or organ system is rare in sarcoidosis, so patients must be thoroughly evaluated…
View Post 5 min This content is machine translated Psoriatic arthritis (PsA) Focus on the risk profile Approximately one-third of patients with psoriasis develop psoriatic arthritis (PsA). The events responsible for progression to PsA are still unclear. However, genetic and clinical demographic risk factors, particularly family aggregation…
View Post 12 min This content is machine translated Axial spondyloarthritis and psoriatic arthritis Effective and efficient against pain The anti-IL-17A monoclonal antibody ixekizumab has already been approved since 2016 for the treatment of moderate to severe plaque psoriasis and psoriatic arthritis. In 2020, axial spondyloarthritis (axSpA) was added… CME-Test
View Post 4 min This content is machine translated Rheumatoid arthritis Translational medicine and omics analyses: focus on proven and new therapeutic approaches In rheumatoid arthritis, the immune system attacks the synovial membrane of the synovium. If left untreated, there is a risk of gradual joint destruction. DMARDs are therefore used in severe…
View Post 11 min This content is machine translated Therapy of rheumatoid arthritis Long-term safety for RA patients under JAK inhibition The treatment of rheumatoid arthritis (RA) has made great progress over the past 20 years. This relates both to the range of drugs available and to developments in terms of… CME-Test
View Post 6 min This content is machine translated Valérie Krafft, Executive Director of the Rheumatism League Switzerland: “Rheumatic diseases still meet with a lot of misunderstanding from the public” The Swiss Rheumatism League has been working for people with rheumatism since 1958. In an interview, Executive Director Valérie Krafft explains how the non-profit organization supports those affected, why the…
View Post 4 min This content is machine translated Psoriatic arthritis (PsA) Guselkumab in joint involvement – successful interim results Long-term data from the pivotal DISCOVER-2 study show that treatment with guselkumab resulted in sustained improvements in joint and skin symptoms and functional capacity over a two-year period in biologic-naïve…
