This content is machine translated Migraine Curbing attacks through proactive measures Migraines can significantly reduce the quality of life of those affected. Early treatment is therefore advisable if the diagnosis is confirmed. Migraine therapy can be divided into three groups: Acute...…
View Post 4 min This content is machine translated Biologics for atopic dermatitis Symptom relief through targeted inhibition of inflammatory signaling pathways Monoclonal antibodies are systems therapeutics that block specific cytokines or receptors and can thus selectively influence individual activation cascades of the immune system. Both dupilumab and tralokinmab – the two…
View Post 5 min This content is machine translated Severe asthma Many antibodies lead to success If asthma patients use an inhaled corticosteroid (ICS) over a longer period of time and in high doses, even the additional combination with a long-acting β2-agonist (LABA) does not respond…
View Post 4 min This content is machine translated Atopic dermatitis: biologics Dupilumab also effective and safe in under 12-year-olds In Switzerland, the approval of the highly effective biologic Dupilumab in the indication area of atopic dermatitis has so far been limited to adult and adolescent patients aged 12 years…
View Post 10 min This content is machine translated Developments in the field of acute leukemias The beginning of a new era in therapy Therapy for AML and ALL is on the move. In the future, it will be much more differentiated. Some new options have already been approved, while others are in development…
View Post 5 min This content is machine translated AAIC in Chicago Is amyloid still tenable as a therapeutic target? Much research has been done in the field of Alzheimer’s disease. Yet, to date, no drug candidate has convincingly translated the battle against beta-amyloid into cognitive benefits across all study…
View Post 7 min This content is machine translated Autoimmune neurological diseases Progress in clarification In the course of the last decades, the range of parameters for the clarification of neurological diseases has increased disproportionately compared to other fields of immunology. Many diseases whose pathogenesis…
View Post 10 min This content is machine translated Options in the relapse therapy of multiple myeloma. What comes after the first line? Factors such as pretreatment, age, patient performance, and comorbidities determine relapse therapy in multiple myeloma. Triple combinations with a proteasome inhibitor and/or an IMID are standard. Antibody therapies also play…
View Post 9 min This content is machine translated Bullous autoimmune dermatoses When the skin and mucous membrane come off Bullous autoimmune dermatoses are a clinically and immunopathologically heterogeneous group of rare autoimmune diseases. In patients of older age with pruritus and bulging blisters, bullous pemphigoid is at the top…
View Post 3 min This content is machine translated Joint SSORL/SSAI Meeting Biologics in asthma and aluminum adjuvants in vaccines The fact that asthma is a very heterogeneous disease is especially true for patients with severe asthma. Additional new drugs are needed mainly for patients whose severe asthma is not…
View Post 3 min This content is machine translated Heavily pretreated multiple myeloma New therapeutic option: an antibody that targets CD38 Results from an ongoing phase II trial of the monoclonal antibody daratumumab were presented at the ASCO Congress. This targets the protein CD38, which is highly expressed on myeloma cells.…
