This content is machine translated Pustular psoriasis What is known about inflammatory mechanisms in PPP and GPP? Pustular psoriasis is characterized by the sudden appearance of small, pus-filled blisters (“pustules”). The clinical, pathological and genetic features of GPP and PPP differ from plaque psoriasis. While in GPP...…
View Post 9 min This content is machine translated Psoriasis in special localizations Tailor-made therapy selection – what, how, where? The classic problem areas of psoriasis such as the scalp, palms of the hands, soles of the feet, nails, face and genital area are also referred to as “difficult to…
View Post 8 min This content is machine translated Psoriasis vulgaris Practice-oriented recommendations for system therapy Fortunately, developments in recent years have led to the effective treatment of many patients with moderate to severe psoriasis. In addition to classical immunosuppressants, several biologics and a small molecule…
View Post 7 min This content is machine translated Dermatomyositis Diagnostics and treatment – a current overview Pathognomonic skin signs of dermatomyositis include heliotrope erythema, Gottron papules, and Gottron signs. The determination of myositis-specific autoantibodies has an increasingly important role in the diagnosis. Regarding treatment options, intravenous…
View Post 3 min This content is machine translated Apremilast Effective reduction of itching in the context of scalp psoriasis Visible pruritic lesions on the scalp are a major stress factor for many psoriasis patients. Topical preparations are used as first-line therapy, but these are not always effective, especially in…
View Post 4 min This content is machine translated Small Molecules Phosphodiesterase-4 as a therapeutic target in psoriasis – an update. The oral PDE-4 inhibitor apremilast has been an established treatment option for moderate to severe chronic plaque psoriasis and psoriatic arthritis for several years. And in a phase IIb study…
View Post 4 min This content is machine translated Inflammatory dermatoses New trends in the system therapy of atopic dermatitis Dupilumab, a highly effective biologic, has recently become available as a second-line therapy for moderate to severe atopic dermatitis. Other targeted therapies are being explored in clinical trials. From the…
View Post 3 min This content is machine translated Apremilast “Real-world evidence” in plaque psoriasis with limited skin involvement. The results of the international multicenter study APPRECIATE show a significant symptom reduction including skin involvement of specific sites. In addition, a significant improvement in quality of life was measurable.
View Post 3 min This content is machine translated Chronic inflammatory skin diseases Positive long-term effects in moderate to severe psoriasis Recently published data from the multicenter LIBERATE study confirm the favorable benefit-risk profile of apremilast with long-term use. This is a significant advance for the treatment options of this patient…
View Post 7 min This content is machine translated 5th Zurich Dermatology Training Days Great variety of topics at the “What’s New” sessions At the 5th Dermatological Training Days in the Kongresshaus Zurich, the so-called “What’s New” sessions took place on Friday afternoon, in which current research results, therapy and diagnostic approaches were…
View Post 4 min This content is machine translated Psoriasis and psoriatic arthritis The need for new therapeutic options is great Recently, a large multinational study investigated the impact of psoriasis and psoriatic arthritis (PsA) on the lives of people with the condition. This showed that various areas of the disease…
