This content is machine translated Merkel cell carcinoma – a highly malignant skin tumor Overview of current guideline recommendations on diagnosis and treatment Merkel cell carcinoma is a rare but aggressive form of skin cancer. It mainly affects older people, with the median age at diagnosis being 75 years. Adjuvant radiotherapy is recommended…
View Post 4 min This content is machine translated 11th European Breast Cancer Conference in Barcelona Screening interval and lymphonodectomy in breast carcinoma. Does the presence of symptoms at the regular breast cancer screening appointment affect the likelihood of detecting breast cancer between two screening appointments? Is lymphonodectomy always necessary in women with…
View Post 12 min This content is machine translated Non-necrotizing granulomas Diagnosis and therapy of sarcoidosis Sarcoidosis is a multisystemic granulomatous disease of as yet unclear etiology. The diagnosis of sarcoidosis is based on the typical clinical presentation and histologic evidence of non-necrotizing epithelioid cell granulomas,…
View Post 10 min This content is machine translated Oral cavity carcinoma Histopathological parameters are important prognostic factors Important risk factors for oral cavity carcinomas in our latitudes are tobacco and alcohol use, chronic infection with high-risk HPV, immunosuppression, and previous tumors in the head and neck region.…
View Post 2 min This content is machine translated Post-irradiation Also useful in case of involvement of fewer lymph nodes? In breast cancer patients with involvement of only a few lymph nodes, post-mastectomy radiation should not be omitted. A large meta-analysis of a total of 22 randomized trials makes clear…
View Post 10 min This content is machine translated Treatment of epithelial ovarian cancer. Slow but steady progress Epithelial ovarian carcinoma is a heterogeneous group of carcinomas that have different etiology, genetics, and thus biological prognosis. In advanced stages (IIB-IV), the standard therapy remains maximal cytoreductive therapy, weighing…
View Post 3 min This content is machine translated WCM Congress Basal cell carcinoma – What therapies are available for advanced forms? New avenues in the treatment of basal cell carcinoma (BCC) are being intensively discussed by current researchers. In particular, the functioning and inhibition of the Hedgehog signaling pathway offers an…
View Post 4 min This content is machine translated ASCO Congress What is the potential of adjuvant therapy and genetic analysis? Current research desiderata on melanoma were presented at this year’s ASCO Congress. Immunotherapy is considered the basis of today’s adjuvant treatment, as radiotherapy is no longer recommended due to too…