This content is machine translated Prurigo and PN Anti-inflammatory antipruritic therapy improves quality of life Which mediators are causally involved in peripheral and central itch sensitization in the context of prurigo and prurigo nodularis (PN) and contribute to the maintenance of pruritus is currently being...…
View Post 6 min This content is machine translated Atopic dermatitis: proven therapeutic principles and innovations From healthcare research to precision medicine In Switzerland, around 20 percent of children are affected by atopic eczema, compared to 4-5 percent of adults. The disease burden of AD is considerable, which is also related to...…
View Post 7 min This content is machine translated Prurigo nodularis and AD Effective itch relief through inhibition of the IL-31 signaling pathway The vicious circle of itching and scratching is a central element in both prurigo nodularis (PN) and atopic dermatitis (AD). Interleukin (IL)-31, often referred to as the “itch cytokine”, has...…
View Post 6 min This content is machine translated Chronic pruritus: “Tour d'horizon” Focus on new anti-inflammatory therapeutic approaches Chronic pruritus is associated with considerable suffering and can occur both as part of classic dermatoses and as a leading symptom of many internal diseases. In chronic prurigo, long-lasting itching...…
View Post 4 min This content is machine translated Biologics for atopic dermatitis Th2 cytokines in focus: proven and new targets The range of antibody therapies for atopic dermatitis (AD) has expanded once again in Europe. In addition to dupilumab and tralokinumab, lebrikizumab is another biologic available in this country that...…
View Post 8 min This content is machine translated Research highlights in atopic dermatitis Innovative therapies – Update 2024 The arsenal of currently researched active substances in the indication area of atopic dermatitis (AD) is considerable. In addition to anti-OX40/OX40L antibodies, CM310, nemolizumab and neurokinin receptor 1 antagonists, there…
View Post 6 min This content is machine translated Chronic prurigo Antipruritic therapy alleviates suffering Chronic prurigo is associated with persistent papules and nodules on the skin and is now defined as a disease in its own right. However, this was not always the case:…
View Post 6 min This content is machine translated Prurigo nodularis Inflammation-promoting pruritogenic cytokines as a therapeutic target There are various triggers for the initial itching in prurigo nodularis (PN). If those affected give in to the scratching impulse, the pruritus intensifies, as this stimulates nerve and inflammatory…
View Post 5 min This content is machine translated Prurigo nodularis New therapeutic approaches are promising Recent research findings indicate that Th2-associated immune cells and cytokines play an important role in the pathogenesis of prurigo nodularis (PN). This is the therapeutic target of the two biologics,…
View Post 6 min This content is machine translated Chronic itching Non-trivial – despite proven and new system therapies Chronic pruritus can occur at any age and affect different groups of patients. A guideline-based approach is advisable in order to determine the cause and provide the best possible treatment…
View Post 4 min This content is machine translated Prurigo nodularis When excruciating itching proves to be persistent – what helps? Chronic prurigo is characterized by an “itch-scratch cycle” and is often associated with high levels of distress. The International Forum for the Study of Itch (IFSI) suggests a stage-adapted multimodal…
