This content is machine translated Urticaria & urticaria-like exanthema Case studies from pediatric dermatology The lifetime prevalence of urticaria is almost 20%. Second-generation antihistamines are also recommended as first-line therapy for pediatric patients. However, pediatric patients with itchy wheals are not always suffering from...…
View Post 6 min This content is machine translated Chronic urticaria “Treat-to-target” approach is underpinned by new findings The treatment arsenal for chronic urticaria includes several 2nd generation antihistamines – still the treatment of first choice – the monoclonal antibody Omalizumab and the immunosuppressant Ciclosporin A as an…
View Post 6 min This content is machine translated Chronic urticaria New guideline – Management of urticaria up-to-date At the beginning of 2022, the new urticaria guideline of the German Society for Allergology and Clinical Immunology and the German Dermatological Society was published. Second-generation antihistamines and omalizumab as…
View Post 4 min This content is machine translated Chronic spontaneous urticaria (csU) Study to detect mast cell-activating IgE autoantigen immune complexes. The pathogenesis of chronic spontaneous urticaria is very complex. In a subpopulation of affected patients, activation of mast cells by IgE plays a crucial role. The question of how autoallergens…
View Post 2 min This content is machine translated Comorbidity Research Chronic urticaria: increased prevalence of mental disorders. According to a secondary analysis, almost one in three patients with chronic urticaria suffers from at least one mental disorder. Sleep-wake cycle impairments are most common, followed by anxiety disorders…
View Post 4 min This content is machine translated Chronic spontaneous urticaria When antihistamines are not enough – ligelizumab soon available in addition to omalizumab? The biologic omalizumab has empirically well-documented efficacy and safety and is considered the treatment of choice in international guidelines for cases of chronic spontaneous urticaria with inadequate response to antihistamines.…
View Post 4 min This content is machine translated Chronic spontaneous urticaria FcεRI as a potential biomarker for treatment response to omalizumab. In patients with chronic spontaneous urticaria, high baseline serum FcεRI levels may be a predictor of response to omalizumab treatment. This is the conclusion of a study presented at the…
View Post 6 min This content is machine translated Chronic spontaneous urticaria (csU) Effectively treating wheals and angioedema – a practice-based update. The therapeutic goal of complete freedom from symptoms is realistic in many cases thanks to the treatment options available today. H1 antihistamines are still considered first-line therapy, and the use…
View Post 5 min This content is machine translated Psoriasis, Atopic Dermatitis, Urticaria “The big three” in dermatology In psoriasis as well as in atopic dermatitis and urticaria, the primary goal of treatment is to achieve symptom control and symptom relief, respectively. The therapy is stage-adapted. Because these…
View Post 5 min This content is machine translated Chronic urticaria In which cases do the guidelines recommend omalizumab? According to the guidelines, omalizumab can be used if therapy with dosed H1 antihistamines does not lead to sufficient relief of symptoms. There is ample evidence of efficacy for this…
View Post 6 min This content is machine translated Memories of an allergist Urticaria after gym classes – What’s behind it? A common subtype of inducible urticaria is cholinergic urticaria. Trigger factor is an increase in body temperature caused by physical exertion, hot baths or warm drinks. Emotionally upset mood is…
