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Allergology and clinical immunology

434 posts
  • This content is machine translated Exogenous allergic alveolitis

Turtled out with the pigeons

A 53-year-old man has been suffering from slowly increasing respiratory symptoms such as cough, chest tightness to shortness of breath for several years. While they initially manifested themselves only after…
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  • 6 min
  • This content is machine translated Atopic dermatitis

Modern systems therapeutics specifically regulate the excessive immune response

The therapeutic landscape for patients with moderate to severe atopic dermatitis is changing. In the multifactorial pathogenesis of this chronic recurrent dermatosis, an impaired immune response plays a central role.…
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  • 3 min
  • This content is machine translated COPD in kidney smokers

Lung sick despite abstinence

Traditionally, tobacco smoke has been considered the classic trigger for chronic obstructive pulmonary disease (COPD). But about half of all COPD cases worldwide are due to non-tobacco-related risk factors. An…
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  • 5 min
  • This content is machine translated Epidemiological study

Dermatophyte infections in children and adults

A German research team evaluated the findings of mycological dermatophyte cultures according to identified pathogen, clinical picture, and sociodemographic factors in a retrospective multicenter study. The 2021 in the Journal…
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  • 5 min
  • This content is machine translated Atopic dermatitis

Tralokinumab – another biologic with an excellent benefit-risk profile

Since the beginning of June this year, tralokinumab – a human monoclonal IgG4 antibody that specifically binds with high affinity to the cytokine IL-13 – has been approved for adults…
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  • 4 min
  • This content is machine translated Hidradenitis suppurativa: study report

Successful treatment demonstrably improves quality of life

Adalimumab (anti-TNF-α) is currently still the only approved biologic for the treatment of moderate to severe hidradenitis suppurativa (HS). In a recent “real world” 52-week study, treatment with adalimumab resulted…
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  • 5 min
  • This content is machine translated Grass pollen allergy

Preventive effects of sublingual immunotherapy greatest in children

Allergen-specific immunotherapy (AIT) is a causal immunomodulatory therapy. Effective hyposensitization can reduce the risk of impending “floor change” in allergic rhinitis. Current clinical studies confirm that allergy sufferers in children…
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  • 4 min
  • This content is machine translated Bullous pemphigoid

Updated European expert guideline published

The Autoimmune blistering diseases Task Force of the European Academy of Dermatology and Venereology (EADV) recently issued new recommendations for the treatment of bullous pemphigoid. The consensus expert opinion is based…
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  • 3 min
  • This content is machine translated Atopic dermatitis

The JAK/STAT pathway as a therapeutic target.

Janus kinase (JAK) inhibitors inhibit signal transduction of numerous proinflammatory cytokines with varying selectivity. With baricitinib, upadacitinib and abrocitinib, three oral JAK inhibitors are currently approved in Switzerland for the…
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  • 6 min
  • This content is machine translated Rosacea: drug therapy

Symptom-oriented treatment strategy – patience pays off

In clinical practice, it has become apparent that the previously used subtype classification inadequately reflects the collective of patients with rosacea. This is because different symptoms often overlap and the…
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  • 4 min
  • This content is machine translated Sublingual immunotherapy (SLIT) in children

Prevent asthma with targeted treatment in allergic rhinitis

The use of allergen-specific immunotherapy – also known as hyposensitization – is used for the causal treatment of IgE-mediated allergies. Studies indicate that in children with allergic rhinitis, sublingual immunotherapy…

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