This content is machine translated Inflammatory dermatoses Innovative topical therapy options for atopic dermatitis. Long-term anti-inflammatory treatment options are needed for sustainable management of chronic recurrent atopic eczema. Apart from topically applicable steroids and calcineurin inhibitors, new drug candidates for topical therapy are in…
View Post 5 min This content is machine translated Severe asthma Many antibodies lead to success If asthma patients use an inhaled corticosteroid (ICS) over a longer period of time and in high doses, even the additional combination with a long-acting β2-agonist (LABA) does not respond…
View Post 4 min This content is machine translated IgE autoreactivity in atopic dermatitis. Study shows association with type 2 comorbidities Atopic dermatitis (AD) is one of the type 2 dominant diseases, caused by complex interactions between genetics and the environment. The role of autoreactive IgE antibodies (auto-IgE) in the pathophysiology of…
View Post 4 min This content is machine translated Psoriasis Tissue-resident memory T cells as “key players”. Immunological memory plays an important role in the pathogenesis of psoriasis. Increasingly, researchers are focusing on tissue resident memory T-cells (TRM cells). This is because the persistence of TRM cells…
View Post 6 min This content is machine translated Chronic urticaria New guideline – Management of urticaria up-to-date At the beginning of 2022, the new urticaria guideline of the German Society for Allergology and Clinical Immunology and the German Dermatological Society was published. Second-generation antihistamines and omalizumab as…
View Post 3 min This content is machine translated Interdisciplinary Case Management If symptoms are nonspecific, also consider multiple chemical sensitivity Multiple Chemical Sensitivity” (MCS) is a subjectively experienced increased sensitivity to chemicals from the environment. Affected persons react with a variety of non-specific complaints. The level of suffering can be…
View Post 5 min This content is machine translated Diagnosis and therapy of chronic pruritus When itching becomes chronic, body and soul suffer – what does the new guideline say? Chronic pruritus is a multidisciplinary leading symptom associated with a high disease burden and great suffering. The updated S2k guideline provides detailed treatment recommendations for specific forms and manifestations of…
View Post 6 min This content is machine translated Atopic dermatitis How modern systems therapies relieve itching The spectrum of systemic agents approved for the treatment of moderate to severe atopic dermatitis has recently expanded, so that there is now a choice of several biologics and Janus…
View Post 4 min This content is machine translated Wound Management Case reports of unusual wound infections Changing environmental conditions such as global warming are playing a role in the genesis of new, previously largely unknown infections. Thanks to state-of-the-art routine and specialized microbiological diagnostics such as…
View Post 4 min This content is machine translated Mast cell activation syndrome (MCAS) Practice-relevant findings up-to-date The enzyme tryptase, which is produced almost exclusively by mast cells, is considered a significant parameter in suspected MCAS. If the event-related increase in tryptase compared with symptom-free intervals exceeds…
View Post 5 min This content is machine translated Risk of anaphylaxis Guideline recommendations up-to-date Anaphylactic reactions are among the most severe and potentially life-threatening dramatic events in allergology. Acute treatment is provided based on international guidelines and textbook recommendations. The updated guideline also takes…
