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Allergology and clinical immunology

434 posts
  • This content is machine translated Asthma as a risk factor

Treatment of allergies during pregnancy

Conditions such as asthma and allergic rhinitis are common in women of childbearing age and can affect up to 30% of this age group. The principle of pharmacological treatment is…
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  • 3 min
  • This content is machine translated Desensitization error

Stung against the wrong stitch

Allergen-specific immunotherapy is established as an immunomodulatory therapy for inhalant and hymenopteran venom allergy. Both subcutaneous injection therapy and the sublingual form of therapy are considered safe, but allergic reactions…
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  • 6 min
  • This content is machine translated Systemic Lupus Erythematosus

New weapons in the fight against SLE

Systemic Lupus Erythematosus (SLE) is often a major challenge not only for those affected, but also for physicians. Despite numerous therapeutic options, treatment is usually a tightrope walk between dangerous…
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  • 4 min
  • This content is machine translated Therapy with Small Molecules

JAK inhibitors in inflammatory dermatoses on the rise

In inflammatory processes of dermatological diseases, pro-inflammatory cytokines play a central role. Therefore they are in focus therapeutic approaches when it comes to breaking critical signaling pathways. In addition to monoclonal…
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  • 4 min
  • This content is machine translated Chronic spontaneous urticaria (csU)

Study to detect mast cell-activating IgE autoantigen immune complexes.

The pathogenesis of chronic spontaneous urticaria is very complex. In a subpopulation of affected patients, activation of mast cells by IgE plays a crucial role. The question of how autoallergens…
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  • 3 min
  • This content is machine translated Corona protection and skin health

Mask dermatitis – expert tips for prophylaxis and treatment

During the corona pandemic, an increase in facial skin lesions was observed due to the wearing of a mouth-nose protection. Wearing an FFP2 protective mask will continue to be recommended…
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  • 2 min
  • This content is machine translated Comorbidity Research

Chronic urticaria: increased prevalence of mental disorders.

According to a secondary analysis, almost one in three patients with chronic urticaria suffers from at least one mental disorder. Sleep-wake cycle impairments are most common, followed by anxiety disorders…
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  • 4 min
  • This content is machine translated Atopic eczema

Consistent basic care according to the soak-and-seal principle

Regularly administered basic care is an important guideline-based component of treatment, regardless of the severity of atopic dermatitis. In addition to regenerating the disturbed barrier function of the skin, xerosis…
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  • 2 min
  • This content is machine translated Chronic nodular prurigo

Pruriginous lesional skin exhibits specific DNA methylation signature

The question of which mechanisms contribute to the chronification of pruritus in chronic nodular prurigo is the subject of current research. It is hoped that new insights will be gained…
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  • 2 min
  • This content is machine translated Moderate to severe atopic dermatitis

“Flares” affect the quality of life

Current empirical data underscore the high “burden of disease” in patients with inadequately controlled atopic dermatitis and indicate that there remains a need for highly effective and subgroup-specific systemic therapies.
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  • 5 min
  • This content is machine translated "Beyond skin"

Tralokinumab: long-term perspectives for patients with atopic dermatitis

An excessive Th2 immune response is characteristic of atopic dermatitis. Biologics specifically interfere with signaling cascades of Th2 inflammatory processes. Recently developed novel drugs include tralokinumab. Meanwhile, impressive efficacy evidence from…

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