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Allergology and clinical immunology

428 posts
  • This content is machine translated Comorbidity Research

Chronic urticaria: increased prevalence of mental disorders.

According to a secondary analysis, almost one in three patients with chronic urticaria suffers from at least one mental disorder. Sleep-wake cycle impairments are most common, followed by anxiety disorders…
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  • 4 min
  • This content is machine translated Atopic eczema

Consistent basic care according to the soak-and-seal principle

Regularly administered basic care is an important guideline-based component of treatment, regardless of the severity of atopic dermatitis. In addition to regenerating the disturbed barrier function of the skin, xerosis…
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  • 2 min
  • This content is machine translated Chronic nodular prurigo

Pruriginous lesional skin exhibits specific DNA methylation signature

The question of which mechanisms contribute to the chronification of pruritus in chronic nodular prurigo is the subject of current research. It is hoped that new insights will be gained…
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  • 2 min
  • This content is machine translated Moderate to severe atopic dermatitis

“Flares” affect the quality of life

Current empirical data underscore the high “burden of disease” in patients with inadequately controlled atopic dermatitis and indicate that there remains a need for highly effective and subgroup-specific systemic therapies.
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  • 5 min
  • This content is machine translated "Beyond skin"

Tralokinumab: long-term perspectives for patients with atopic dermatitis

An excessive Th2 immune response is characteristic of atopic dermatitis. Biologics specifically interfere with signaling cascades of Th2 inflammatory processes. Recently developed novel drugs include tralokinumab. Meanwhile, impressive efficacy evidence from…
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  • 3 min
  • This content is machine translated Primary immunodeficiency

Adventure with IGI – Primary immunodeficiency explained in a playful way

With young patients, it is often a challenge for the physician to explain a complex disease in an understandable way to parents and child. On the new website www.leben-mit-pid.ch, the…
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  • 4 min
  • This content is machine translated Dupilumab in atopic dermatitis

New post-hoc analysis: consistent symptom improvement over 52 weeks.

In atopic dermatitis, long-term symptom control is one of the overriding therapeutic goals. A recently published post-hoc analysis demonstrated that patients treated with dupilumab achieved sustained and consistent improvement in…
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  • 3 min
  • This content is machine translated Case Report

Subcorneal pustular dermatosis

Also known as Sneddon-Wilkinson syndrome, this rare disorder is characterized by primary pustular changes predominantly in the trunk and proximal extremities. Histopathologic examination complementary to physical inspection and history allows…
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  • 4 min
  • This content is machine translated Moderate to severe atopic dermatitis

IL-13 blockade – an innovative treatment approach with great potential

The spectrum of systemic treatment options for atopic dermatitis is currently in flux. In recent years, the interleukin (IL)-13 pathway has been shown to play an essential role in the…
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  • 4 min
  • This content is machine translated Upper respiratory tract comorbidities

When asthma and rhinosinusitis go hand in hand

Almost half (45%) of all patients with – mainly severe – asthma are also affected by chronic rhinosinusitis with nasal polyps (CRSwNP). As many as 60% have allergic rhinitis as a…
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  • 5 min
  • This content is machine translated New S3 guideline

Clear focus on primary allergy prevention

When it comes to allergy prevention, what are the priorities for supplemental feeding? How should the administration of cow’s milk-based formula be evaluated? Are supplements a reliable preventive measure? And…

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