This content is machine translated Neurodermatitis in children and adolescents Consistent topical basic care – the foundation of every successful therapy Pathophysiologically, a disturbed skin barrier with a lack of natural moisturizing factors and altered lipid and protein composition plays a key role in atopic dermatitis. Restoring physiological skin barrier function…
View Post 11 min This content is machine translated Atopic dermatitis The role of the key cytokine IL-13 The Th2 response of atopic dermatitis is strongly controlled by IL-13, which activates the type II receptor by binding to the IL-13Rα chain. IL-13 is expressed at higher levels than… CME-Test
View Post 4 min This content is machine translated Chronic spontaneous urticaria FcεRI as a potential biomarker for treatment response to omalizumab. In patients with chronic spontaneous urticaria, high baseline serum FcεRI levels may be a predictor of response to omalizumab treatment. This is the conclusion of a study presented at the…
View Post 5 min This content is machine translated Pollen allergy Specific subcutaneous immunotherapy – What’s new? Specific immunotherapy (SIT) is the only disease-modifying and curative form of therapy for the treatment of immediate-type allergies. In contrast to symptomatic pharmacological therapies, SIT pursues the goal of sustained…
View Post 4 min This content is machine translated Moderate to severe atopic dermatitis JAK inhibitor upadacitinib a clear winner in comparative study with dupilumab The development of innovative drugs for the treatment of atopic dermatitis (AD) is increasingly focused on targeted therapies that selectively interfere with disease-causing signaling pathways [1]. That the Janus kinase…
View Post 6 min This content is machine translated Chronic spontaneous urticaria (csU) Effectively treating wheals and angioedema – a practice-based update. The therapeutic goal of complete freedom from symptoms is realistic in many cases thanks to the treatment options available today. H1 antihistamines are still considered first-line therapy, and the use…
View Post 5 min This content is machine translated Psoriasis, Atopic Dermatitis, Urticaria “The big three” in dermatology In psoriasis as well as in atopic dermatitis and urticaria, the primary goal of treatment is to achieve symptom control and symptom relief, respectively. The therapy is stage-adapted. Because these…
View Post 4 min This content is machine translated Swiss Vaccination Plan 2021 Vaccination in chronic diseases – an update Vaccinations for other vaccine-preventable infections should not be neglected during the corona pandemic. Various congenital, disease-acquired, and iatrogenically induced conditions are associated with immune system suppression and therefore require consideration…
View Post 5 min This content is machine translated Moderate to severe atopic dermatitis Biologic therapy in the changing times: “Best practice” approaches in focus In addition to the new systemic drugs recently launched, several active substances are currently in development. These include some biologics in advanced stages of clinical testing. Overall, the future prospects…
View Post 4 min This content is machine translated Atopic dermatitis JAK inhibition as a mode of action – an update. Janus kinase (JAK) inhibitors are a promising new treatment option for adult patients with atopic eczema, given their rapid relief of pruritus and inflammatory lesions. In addition to baricitinib, which…
View Post 4 min This content is machine translated Allergic rhinitis Nose runs – research too Allergic rhinitis (AR) is one of the most common diseases in the world with an incidence of 10% to 40% in the population. Upper respiratory tract disease is manifested by…