This content is machine translated Chronic spontaneous urticaria (csU) Study to detect mast cell-activating IgE autoantigen immune complexes. The pathogenesis of chronic spontaneous urticaria is very complex. In a subpopulation of affected patients, activation of mast cells by IgE plays a crucial role. The question of how autoallergens…
View Post 3 min This content is machine translated Corona protection and skin health Mask dermatitis – expert tips for prophylaxis and treatment During the corona pandemic, an increase in facial skin lesions was observed due to the wearing of a mouth-nose protection. Wearing an FFP2 protective mask will continue to be recommended…
View Post 2 min This content is machine translated Comorbidity Research Chronic urticaria: increased prevalence of mental disorders. According to a secondary analysis, almost one in three patients with chronic urticaria suffers from at least one mental disorder. Sleep-wake cycle impairments are most common, followed by anxiety disorders…
View Post 4 min This content is machine translated Atopic eczema Consistent basic care according to the soak-and-seal principle Regularly administered basic care is an important guideline-based component of treatment, regardless of the severity of atopic dermatitis. In addition to regenerating the disturbed barrier function of the skin, xerosis…
View Post 2 min This content is machine translated Chronic nodular prurigo Pruriginous lesional skin exhibits specific DNA methylation signature The question of which mechanisms contribute to the chronification of pruritus in chronic nodular prurigo is the subject of current research. It is hoped that new insights will be gained…
View Post 2 min This content is machine translated Moderate to severe atopic dermatitis “Flares” affect the quality of life Current empirical data underscore the high “burden of disease” in patients with inadequately controlled atopic dermatitis and indicate that there remains a need for highly effective and subgroup-specific systemic therapies.
View Post 5 min This content is machine translated "Beyond skin" Tralokinumab: long-term perspectives for patients with atopic dermatitis An excessive Th2 immune response is characteristic of atopic dermatitis. Biologics specifically interfere with signaling cascades of Th2 inflammatory processes. Recently developed novel drugs include tralokinumab. Meanwhile, impressive efficacy evidence from…
View Post 4 min This content is machine translated Dupilumab in atopic dermatitis New post-hoc analysis: consistent symptom improvement over 52 weeks. In atopic dermatitis, long-term symptom control is one of the overriding therapeutic goals. A recently published post-hoc analysis demonstrated that patients treated with dupilumab achieved sustained and consistent improvement in…
View Post 3 min This content is machine translated Case Report Subcorneal pustular dermatosis Also known as Sneddon-Wilkinson syndrome, this rare disorder is characterized by primary pustular changes predominantly in the trunk and proximal extremities. Histopathologic examination complementary to physical inspection and history allows…
View Post 4 min This content is machine translated Moderate to severe atopic dermatitis IL-13 blockade – an innovative treatment approach with great potential The spectrum of systemic treatment options for atopic dermatitis is currently in flux. In recent years, the interleukin (IL)-13 pathway has been shown to play an essential role in the…
View Post 4 min This content is machine translated Upper respiratory tract comorbidities When asthma and rhinosinusitis go hand in hand Almost half (45%) of all patients with – mainly severe – asthma are also affected by chronic rhinosinusitis with nasal polyps (CRSwNP). As many as 60% have allergic rhinitis as a…
