This content is machine translated Atopic dermatitis Focus on mediators of type 2 inflammation The pathomechanisms of atopic dermatitis (AD) are becoming increasingly better understood. A genetically determined immunological imbalance is characterized by an increased Th2 response and is associated with the production of…
View Post 3 min This content is machine translated Journal Club Atopic dermatitis and the skin microbiome: new study findings Exploring the links between the cutaneous microbiome and the severity of atopic dermatitis (AD) and patient-related co-factors is an important aspect in the development of new personalized AD therapies, especially…
View Post 6 min This content is machine translated Chronic urticaria “Treat-to-target” approach is underpinned by new findings The treatment arsenal for chronic urticaria includes several 2nd generation antihistamines – still the treatment of first choice – the monoclonal antibody Omalizumab and the immunosuppressant Ciclosporin A as an…
View Post 5 min This content is machine translated Case reports: Pityriasis rubra pilaris (PRP) Supposedly therapy-resistant PRP responded to biologic treatment The treatment of pityriasis rubra pilaris can be a challenge. The therapeutic arsenal includes topical corticosteroids, phototherapy or classic systemic therapies such as retinoids or immunosuppressants. Recent case reports and…
View Post 5 min This content is machine translated Prurigo nodularis New therapeutic approaches are promising Recent research findings indicate that Th2-associated immune cells and cytokines play an important role in the pathogenesis of prurigo nodularis (PN). This is the therapeutic target of the two biologics,…
View Post 7 min This content is machine translated Update allergology Management of allergies in the era of precision medicine In the context of molecular allergy diagnostics, IgE antibodies against individual allergen components are determined. This offers added value, especially for patients with multiple sensitizations. Allergen-specific immunotherapy is available in…
View Post 16 min This content is machine translated Invasive pulmonary aspergillosis Correctly diagnose and treat IPA Aspergillus species can cause a variety of diseases. Among these, invasive pulmonary aspergillosis (IPA) is the most common opportunistic infection caused by moulds in immunocompromised patients and is characterized by… CME-Test
View Post 3 min This content is machine translated Study Report Dupilumab in 6- to 11-year-old AD patients: Effects on skin barrier function Atopic dermatitis (AD) is one of the most common diseases in childhood and adolescence. An observational study evaluated the effects of dupilumab in a subpopulation of 6–11-year-old patients with moderate-to-severe…
View Post 15 min This content is machine translated Hidradenitis suppurativa Etiopathogenesis, diagnosis and treatment – an update The pathogenesis of hidradenitis suppurativa (HS) has not yet been fully clarified; it is assumed that there are multifactorial interactions. The most important risk factors and comorbidities include smoking, obesity… CME-Test
View Post 7 min This content is machine translated Teledermatology Evaluation of patient satisfaction Overall, the spread and acceptance of telemedicine services have increased in recent years. As a strongly visual subject, dermatology is particularly well suited for telemedicine applications. International studies show a…
View Post 4 min This content is machine translated Crohn's disease in remission Avoid infliximab only with caution Patients with Crohn’s disease can be effectively placed in clinical remission with the combination of infliximab and immunosuppressants. However, long-term use poses some dangers. Scientists from Liege have therefore investigated…
