This content is machine translated Actinic keratoses Precancerous light skin – what are risk factors for progression? Actinic keratoses (AK) are associated with squamous cell carcinoma, but little is known about the risk of progression of individual lesions. However, field carcinogenesis or a higher number of lesions…
View Post 6 min This content is machine translated Chronic itching Non-trivial – despite proven and new system therapies Chronic pruritus can occur at any age and affect different groups of patients. A guideline-based approach is advisable in order to determine the cause and provide the best possible treatment…
View Post 4 min This content is machine translated Chronic myeloid leukemia (CML) Transcript types, molecular response and biomarkers on the test bench. Chronic myeloid leukemia is a model disease for diagnosis and therapy of neoplastic diseases. The underlying cytogenetic aberration and the multistage progression enable the transfer of molecular cytogenetic findings into…
View Post 5 min This content is machine translated Implement KDIGO guidelines CKD in type 2 diabetes – from screening to patient-centered care Treatment options for patients with diabetes and chronic kidney disease (CKD) have improved significantly thanks to new therapeutic options from the SGLT-2-i, GLP-1-RA and MRA drug classes. The new guidelines…
View Post 6 min This content is machine translated Pulmonary arterial hypertension (PAH) Results of the Phase III STELLAR study show therapeutic progress In pulmonary arterial hypertension, sotatercept improved primary and secondary endpoints, and thus numerous disease parameters, in a phase 3 study, in addition to standard combination therapy. The molecule targets a…
View Post 3 min This content is machine translated Hereditary angioedema New Real-World Data on Long-Term Prophylaxis Hereditary angioedema (HAE) is a rare genetic disorder that causes recurrent swelling of the skin, mucous membranes, or various internal organs at irregular intervals. International guidelines recommend long-term prophylaxis with…
View Post 6 min This content is machine translated Chronic rhinosinusitis Endotyping as a basis for targeted treatment In particular, chronic rhinosinusitis with polyposis nasi (CRSwNP) is often associated with high levels of distress and personalized therapeutic strategies are required. Improved understanding of the immunological and inflammatory genesis…
View Post 4 min This content is machine translated Do low carb diets harm the heart? Keto diet associated with hypercholesterolemia and increased risk of ASCVD Many people think they are doing something good for their health with a low carb high fat diet. However, adherence to a low-carbohydrate, high-fat so-called ketogenic diet has now been…
View Post 4 min This content is machine translated Multiple Myeloma (MM) Prognostic factors, the role of leptin and MGUS in focus. Multiple myeloma results from the degeneration of a single plasma cell whose clones spread throughout the bone marrow. Overall, the disease occurs very rarely. However, it is one of the…
View Post 3 min This content is machine translated Fatty liver disease New widespread disease NAFLD Model calculations suggest that the number of patients with cirrhosis, advanced fibrosis, or hepatocellular carcinoma (HCC) could double to triple in the next 10-15 years. Not least because of this,…
View Post 6 min This content is machine translated Allergen immunotherapy (AIT) Adherence is crucial for treatment success Allergen-specific immunotherapy can prevent disease progression in the long term by tolerance development in allergic diseases. However, to achieve sustainable effects, long-term therapy is required, which requires a certain degree…
