This content is machine translated Epidermolysis bullosa Wound chronicity and tumorigenesis – relevance of T cell-mediated mechanisms. Bullous autoimmune dermatoses result from an autoantibody-driven immune response against structural proteins of the skin. Chronic wounds in the setting of recessively inherited dystrophic epidermolysis bullosa (RDEB) are highly susceptible…
View Post 3 min This content is machine translated Hypertension Systemic thinking, individualized treatment Hypertension is a widespread disease that primarily affects people of advanced age. Reducing levels to the target range requires comprehensive treatment management consisting of lifestyle modification and pharmacotherapy. If this…
View Post 7 min This content is machine translated Neuro-Oncology The therapy of brain tumors in the light of new findings Neuro-oncology specializes in the diagnosis and treatment of cancers of the central nervous system. Her main focus is on primary brain tumors such as gliomas or meningiomas, but she also…
View Post 3 min This content is machine translated Reflux Endoscopy – necessary or superfluous? Heartburn and acid regurgitation are symptoms that are a common cause for presentation to the primary care physician’s office. If there are no other complaints, however, an endoscopy can usually…
View Post 4 min This content is machine translated System therapy for atopic dermatitis: biologics or JAK inhibitors? Balancing benefits and risks The era of targeted systemic treatment began several years ago and the therapy armamentarium is constantly expanding, so that the question of selection criteria for the individually appropriate therapy is…
View Post 7 min This content is machine translated Epilepsy Freedom from seizures with a good quality of life for all affected persons The biennial joint meeting of the professional societies from Germany, Austria and Switzerland is the fourth largest meeting on epilepsy worldwide. In German-speaking countries, both the quality of care for…
View Post 5 min This content is machine translated Systemic mastocytosis Diagnostics and drug therapy approaches – an update A KIT mutation analysis from the bone marrow is recommended in the case of highly elevated tryptase levels. In particular, adults often have a point mutation in codon 816 of…
View Post 6 min This content is machine translated Patient-adapted diabetes therapy “Time in Range” and AID systems gain in importance Both continuous glucose monitoring (CGM) systems and sensor-assisted insulin therapy are already widely available. Devices for automated insulin delivery (AID) such as hybrid or closed loop AID will play an…
View Post 4 min This content is machine translated Sleep disorders Sleep parameters as signposts for brain functions People who sleep poorly feel tired and listless during the day. Mild sleep problems are probably familiar to everyone. But sufferers with manifest sleep disorders suffer from a variety of…
View Post 8 min This content is machine translated Psoriasis The era of biologics – a tour d’horizon through significant research decades The development of highly effective biologics was preceded by research efforts over several decades. Advances in immunopathogenetic and molecular genetic analyses contributed significantly to the generation of these innovative system…
View Post 4 min This content is machine translated Hypothyroidism L-thyroxine monotherapy is still considered the standard of care Patients with elevated TSH values should be evaluated for possible hypothyroidism, taking into account the respective reference standard value ranges and intra- and interindividual variability. In patients with hypothyroidism requiring…
