This content is machine translated Lupus nephritis Special case kidney For a long time, the treatment of lupus was characterized by stagnation. However, after 20 years of frustration, there is finally movement to develop new therapeutic options. Studies have produced promising results…
View Post 6 min This content is machine translated Therapy of metastatic HER2-positive breast carcinoma Is a cure possible soon? In recent years, the prognosis of metastatic HER2-positive breast carcinoma has been significantly improved by the development of new agents such as the antibody-drug conjugate (ADC) trastuzumab-deruxtecan and the HER2-targeted…
View Post 3 min This content is machine translated Pediatric operations When children wish for more pain medication Postoperative pain and pain-related impairments are still inadequately treated in many cases, not only in adults but also in children. In an analysis of pediatric patient populations, a group of…
View Post 4 min This content is machine translated Lipid management: LDL cholesterol reduction Add-on to statin therapy recommended in patients at high cardiovascular risk Numerous empirical studies confirm that there is a causal relationship between high LDL cholesterol levels and cardiac events. The current motto with regard to LDL cholesterol reduction is “the lower,…
View Post 3 min This content is machine translated Parkinson's disease Effective therapy management: mastering challenges An effective treatment regimen in PD is closely linked to a personalized approach. Depending on the age of onset and subtype of the disease, the challenges are different. In addition…
View Post 5 min This content is machine translated Myelofibrosis Treatment in transition With the introduction of the Janus kinase (JAK) inhibitor ruxolitinib, therapy for myelofibrosis has changed dramatically in recent years. Nevertheless, further innovation is needed, especially in the second line. Promising…
View Post 6 min This content is machine translated Diabetic polyneuropathy Measure nerve conduction velocity for diagnosis Diabetic polyneuropathy (dPNP) is the most common neuropathy in Western countries. But who gets them and how do you recognize them? This question is particularly important because 40% of those…
View Post 2 min This content is machine translated Lipid Management Guideline-compliant care up to date A fundamental factor in the field of cardiology is LDL cholesterol. Because without cholesterol, there is no atherosclerosis. Therefore, effective lipid management is paramount for the prevention of cardiovascular events.…
View Post 4 min This content is machine translated Acute generalized exanthematous pustulosis (AGEP). Not just a T cell-mediated disease? Immunopathological studies have shown that not only T cells play a role in drug reactions, especially in AGEP, but also IL36 cytokines and other mediators are involved. These findings are…
View Post 6 min This content is machine translated Connective tissue diseases Early detection and treatment of localized scleroderma in children In progressive forms and extensive linear expression of the lesions, deformities and movement restrictions may occur if left untreated. Early diagnosis enables adequate treatment measures and sustainable long-term management. This…
View Post 4 min This content is machine translated Digital Health Technology Artificial Intelligence and “Big Data” – also a trend in dermatology Especially in the field of medical image recognition, artificial intelligence (AI) applications are widely developed, which is a very interesting application area for dermatology. For an adequate implementation of digital…