This content is machine translated Paroxysmal nocturnal hemoglobinuria Real-world data on thrombosis predictors and C5 complement inhibitors Paroxysmal nocturnal haemoglobinuria (PNH) is a rare, acquired disease of haematopoietic stem cells of the bone marrow. GPI deficiency results in the absence of complement-regulating proteins. Thromboembolic complications are the...…
View Post 5 min This content is machine translated Glomerulonephritis: IgA nephropathy Pathogenesis-based and nephroprotective therapeutic approaches Immunoglobulin (Ig) A nephropathy is considered an important cause of end-stage renal failure. Therefore, from today’s perspective, IgA nephropathy should not be classified as a benign disease. Fortunately, the treatment...…
View Post 4 min This content is machine translated Current findings on myelofibrosis Reduce anemia and transfusion dependency Myelofibrosis (MF) is a rare clonal disease of pluripotent hematopoietic stem and progenitor cells. There have been significant advances in the treatment options for MF in recent years, but anemia...…
View Post 6 min This content is machine translated Postmenopausal osteoporosis: long-term therapy concepts Targeted use of antiresorptives and osteoanabolic agents and avoid “rebound” effects Postmenopausal osteoporosis in women is a consequence of decreasing oestrogen levels and is associated with rapid bone loss (“high-turnover osteoporosis”). Long-term therapy concepts are required to achieve sustainable effects –...…
View Post 8 min This content is machine translated Atopic dermatitis Implement the “minimal disease activity” concept Minimal disease activity (MDA) in atopic dermatitis (AD) is a concept that combines a treat-to-target therapeutic strategy with the principle of shared decision-making. The aim is to achieve a state...…
View Post 6 min This content is machine translated Sensation of pain Special features for people with multiple disabilities Patients with multiple disabilities are affected by pain of various kinds due to a wide range of acute and chronic illnesses. People who are unable to adequately articulate their complaints...…
View Post 6 min This content is machine translated Chronic musculoskeletal pain How can the use of analgesics be optimized in multimodal therapy? Musculoskeletal pain is complex and often underestimated. Pain sensitization plays an important role in chronification. In the long-term use of currently available analgesics, there may be conflicting goals with regard...…
View Post 2 min This content is machine translated Chronic pain Nano-ECS modulator Adezunap improves therapy success Cannabinoids have established themselves as therapeutic options in the treatment of pain in recent years. Nevertheless, patients can experience problems when using them, particularly with regard to tolerance. A new...…
View Post 8 min This content is machine translated Psoriasis and PsA Biologics, oral peptide and trivalent nanobody – current results and trends Top-line results are available for both Icotrokinra and Sonelokimab, which attest to the great therapeutic potential of these innovative drug candidates. However, there is also extremely interesting new evidence from...…
View Post 6 min This content is machine translated Wound management: clinical diagnostics Assessing the risk of infection – from the ABCDE to the TILI score Chronic wounds pose a challenge for both those affected and those treating them. The risk of bloodstream infections or sepsis is increased due to various factors. Early diagnosis of wound...…
View Post 8 min This content is machine translated ASCO 2025 Supportive therapies for greater adherence and compliance ASCO 2025 is the annual meeting of the American Society of Clinical Oncology (ASCO), which took place in Chicago from May 30 to June 3. In this section, we take...…
