This content is machine translated Uveal melanoma Development of a CAR T-cell therapy for uveal melanoma T cells that are endowed with tumor specificity through the expression of a chimeric antigen recept or (CAR) are becoming increasingly important. They are already increasingly being used in adoptive… CME-Test
View Post 4 min This content is machine translated AI-based skin cancer diagnostics How do algorithms make complex decisions? Artificial intelligence (AI) can help to detect skin cancer in everyday clinical practice, but one hurdle is that the decisions made by algorithms are often not comprehensible. Scientists at the…
View Post 7 min This content is machine translated Acne vulgaris Multifactorial etiopathogenesis – an update The scientific advances of the last few decades have contributed significantly to our understanding of the pathogenesis of acne and the further development of treatment options based on this. According…
View Post 3 min This content is machine translated Differential diagnosis of psoriasis vs. eczema Molecular classifier for unclear cases – an interim assessment In everyday clinical practice, eczema or psoriasis are often diagnosed at a glance. In clinically inconclusive cases, histological examination can provide valuable information, but it is not uncommon for clinically…
View Post 4 min This content is machine translated Rosacea Alleviating symptoms via molecular and cellular targets Although the pathophysiological mechanisms of rosacea are not yet fully understood, there are consensus-based explanatory models. Consequently, the etiopathogenesis is multifactorial, with genetic and environmental components. The treatment should be…
View Post 4 min This content is machine translated Seborrheic dermatitis Intensify and combine therapy depending on persistence In addition to antifungal shampoos for scalp infestations, topical preparations with keratolytic and anti-inflammatory properties are among the classic measures for seborrhoeic eczema. In adults and older children, products containing…
View Post 11 min This content is machine translated Family medicine for refugees Meeting special requirements People who arrive at the federal initial processing centers (Bundeasylzentren/BAZ) have very different biographies and migration histories. What they have in common, however, is the hope of receiving medical care… CME-Test
View Post 4 min This content is machine translated Rare vasculitides - polyarteritis nodosa (PAN) Hepatitis B has lost in diagnostics, proteinuria has won Polyarteritis Nodosa (PAN) is a vasculitis of medium and small vessels. The incidence is estimated at 1.6 to 1.9 cases per million inhabitants per year, which is probably one reason…
View Post 5 min This content is machine translated Biologics therapy for psoriasis Better outcomes through innovative methods of therapy management Personalized medicine is also becoming increasingly important in the field of inflammatory skin diseases. Currently, IL-17 and IL-23 inhibitors are most effective in moderate to severe psoriasis, but the response…
View Post 4 min This content is machine translated Systemic lupus erythematosus Protection against relapses, even without remission The line between low disease activity and remission in systemic lupus erythematosus is often imprecise. The question remains to what extent this can play a role for outcomes such as…
View Post 6 min This content is machine translated Prurigo nodularis Inflammation-promoting pruritogenic cytokines as a therapeutic target There are various triggers for the initial itching in prurigo nodularis (PN). If those affected give in to the scratching impulse, the pruritus intensifies, as this stimulates nerve and inflammatory…