This content is machine translated From genome profiles to targeted therapies Advances in breast cancer therapy in the age of molecular diagnostics The treatment of breast cancer has undergone a profound transformation over the last two decades. While clinical-pathological parameters long formed the sole basis for therapy decisions, molecular diagnostics and personalized...…
View Post 6 min This content is machine translated Current overview of evidence, mechanisms and clinical implications Apolipoprotein E and neuropsychiatric symptoms in neurocognitive disorders Neuropsychiatric symptoms (NPS) such as depression, anxiety, apathy, psychosis or behavioral disorders are among the most common concomitant symptoms of neurocognitive disorders and have just as strong an impact on...…
View Post 6 min This content is machine translated Latent autoimmune diabetes in adults (LADA) Looks like type 2, but is type 1 Type 1 diabetes can occur in any age group. In adults, however, type 2 diabetes (T2DM) is often diagnosed first, and autoantibodies indicative of T1DM are only detected later. The...…
View Post 6 min This content is machine translated Update on diagnostics, risk stratification and therapy Acute myeloid leukemia 2025 Acute myeloid leukemia (AML) remains one of the greatest challenges in hematology. Despite established chemotherapy protocols, the prognosis for many patients remains unfavorable. In recent years, however, new molecular classifications,...…
View Post 3 min This content is machine translated Case report: Acute rheumatic fever ARF with myocarditis and occlusion of the RCA Acute rheumatic fever (ARF) and rheumatic heart disease continue to pose a serious health risk in most developing countries. In individual cases, however, it also occurs in industrialized countries. ARF...…
View Post 5 min This content is machine translated Systemic lupus erythematosus Increased risk of pulmonary manifestations Previous studies have shown that individuals with newly diagnosed systemic lupus erythematosus (SLE) have an increased risk of pulmonary complications. However, these analyses did not consistently account for potential confounding...…
View Post 6 min This content is machine translated Late-onset rheumatoid arthritis More DMARDs can reduce glucocorticoids in LORA Although glucocorticoids have no influence on the course of the disease, they are effective agents against symptomatic pain and inflammation in rheumatoid arthritis (RA). Patients with late onset RA (LORA)...…
View Post 5 min This content is machine translated Case study Opportunistic infection by Serratia marcescens Immunocompromised individuals sometimes have a considerably increased risk of opportunistic infections. Serratia marcescens is a Gram-negative bacterium that belongs to the Enterobacteriaceae family and was identified as the pathogen in...…
View Post 3 min This content is machine translated From symptom to diagnosis Abdominal pain – groin pain: internal causes Imaging procedures – in particular computed tomography (CT) and magnetic resonance imaging (MRI) with and without contrast enhancement – are informative in the differential diagnosis of groin pain. The spectrum...…
View Post 6 min This content is machine translated An underestimated risk with clear consequences for clinical practice Smoking and diabetic nephropathy Diabetic nephropathy is one of the most serious complications of diabetes mellitus. It is not only a central cause of terminal renal insufficiency, but is also closely linked to cardiovascular...…
View Post 4 min This content is machine translated Gastrointestinal complaints PPI regulation under the microscope Proton pump inhibitors (PPIs) are very effective and suitable for certain indications and treatment periods, but there is an increasing trend towards “off-label” prescriptions. To ensure that temporary administration for...…
