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Geriatrics

369 posts
  • This content is machine translated Hormone balance and longevity

Ageing is not a substitution diagnosis

In the longevity debate, “hormone balance” is often used as a synonym for “biologically younger”. Clinically, the term is only meaningful if it is linked to clearly defined axial disorders,...…
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  • 7 min
  • This content is machine translated Chronic inflammation as a driver of ageing

Immunosenescence and inflammaging

Immunosenescence and inflammaging are now regarded as central biological mechanisms of ageing. The age-related altered immune system is both weakened and chronically activated – with consequences for susceptibility to infection,...…
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  • 5 min
  • This content is machine translated Side effects under opioid therapy

Is it possible to avoid the inevitable?

Opioid analgesics are an essential tool for the relief of cancer-related pain. However, in addition to their undeniable therapeutic value, opioids are associated with a number of predictable side effects...…
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  • 3 min
  • This content is machine translated Ginkgo biloba extract in the Alzheimer's mouse model

Effects on disease-associated microglia subpopulations

During the progression of Alzheimer’s disease, microglial cells located in the vicinity of plaques become overactivated and release cytotoxic mediators such as TNFα. In an animal study published in 2025,...…
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  • 12 min
  • This content is machine translated Palliative care symptom and needs assessment.

What screening tools are helpful?

In view of the new and mostly well-tolerated therapies, the palliative life and treatment time of oncological patients is increasingly extended. It is a major challenge to identify patients in...…
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  • 15 min
  • This content is machine translated Diabetes mellitus

Treatment of comorbidities in older people

One in five people over 65 and one in four people over 75 are affected by diabetes. Global projections predict a 2.5-fold increase in diabetes prevalence over the next 25...…
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  • 15 min
  • This content is machine translated Diabetes mellitus

Treatment of comorbidities in older people

One in five people over 65 and one in four people over 75 are affected by diabetes. Global projections predict a 2.5-fold increase in diabetes prevalence over the next 25...…
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  • 4 min
  • Education
  • Geriatrics
  • Neurology
  • Pharmacology and toxicology
  • RX
  • Studies

Opicapon: double benefit for motor function and sleep in Parkinson’s disease

Sleep disorders are among the most common non-motor Parkinson’s symptoms. The targeted treatment of sleep disorders is an important part of Parkinson’s therapy and can significantly improve quality of life....…
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  • 5 min
  • This content is machine translated "Survey of Health, Ageing and Retirement in Europe" (SHARE)

Analysis of polypharmacy in ≥65-year-olds

The SHARE study is an international multidisciplinary longitudinal survey. The panel survey has been conducted approximately every other year for over 20 years. In an analysis published in 2025, data...…
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  • 8 min
  • This content is machine translated New perspectives for clinics and research

Ageing, cellular senescence and Parkinson’s disease

Parkinson’s is one of the most common neurodegenerative diseases and continues to pose major challenges for neurology. It has long been clear that age is the decisive risk factor –...…
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  • 7 min
  • This content is machine translated Wound Care

Chronically infected wound on the lower leg – a case report

Prof. Dr. Sebastian Probst and Prof. Dr. Ewa-Klara Stürmer used the case study of an 85-year-old patient with a CVI-dominated “mixed leg ulcer” to illustrate the problem of chronic stagnant...…

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