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Hematology

264 posts
  • This content is machine translated Childhood cancer

Progress made in recent years does not reach everyone

Early death after childhood cancer diagnosis remains a challenge. Infants, ethnic minorities, and the socioeconomically worse off are at higher risk for early death. The reasons for this need to…
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  • 7 min
  • This content is machine translated Therapy for initial diagnosis of multiple myeloma

Treatment protocols in the age of modern substances

We are in the era of new efficient compounds against multiple myeloma. Nevertheless, high-dose chemotherapy followed by autologous stem cell transplantation remains an essential part of the first-line treatment of…
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  • 8 min
  • This content is machine translated Multiple Myeloma

Pathogenesis, clinic, diagnostics

In multiple myeloma, the clinic leading to the diagnosis is derived from the end-organ damage. The diagnostic criteria were last updated in 2014. With well-established and widely available diagnostics, the…
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  • 5 min
  • This content is machine translated EHA Congress in Madrid

Earlier response does not translate into higher overall survival in CML

Overall survival of patients with chronic myeloid leukemia cannot be altered by optimizations of imatinib therapy. This is despite the fact that earlier evaluations were able to demonstrate an influence…
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  • 5 min
  • This content is machine translated ICML 2017 in Lugano

Long-term data are positive

At the ICML Congress, the audience gained insight into long-term data from two phase III trials in mantle cell lymphoma and chronic lymphocytic leukemia. The new results confirm the statements…
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  • 7 min
  • This content is machine translated 10th Iron Academy, Zurich

Iron deficiency in pregnancy and postpartum

In Switzerland, about 32% of all pregnant women have an iron deficiency, which together with the resulting anemia can cause complications for mother and child. Oral and intravenous iron preparations…
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  • 3 min
  • This content is machine translated Acute lymphoblastic leukemia

Bispecific antibody in heavily pretreated patients.

Blinatumomab forms a bridge between T cells and cancer cells. The bispecific antibody is proving its worth in a new phase III trial. It has been approved in Switzerland for…
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  • 7 min
  • This content is machine translated Treatment of hemophilia

New techniques to extend the half-life

Prophylactic treatment with factor concentrates is now standard in the treatment of patients with severe hemophilia A. Conventional factor VIII and factor IX concentrates have a relatively short half-life and…
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  • 5 min
  • This content is machine translated ASH 2016 in San Diego

Multiple Myeloma Review

As every year, the ASH Congress took place in the busy pre-Christmas season. This time, experts from hematology and oncology met in San Diego. Multiple myeloma was again an important…
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  • 10 min
  • This content is machine translated Preoperative anemia in the era of patient blood management (PBM).

A pragmatic approach to diagnostics and therapy

Preoperative anemia is an independent predictor of increased risk of infection, thromboembolism, and mortality. For their part, allogeneic blood transfusions further contribute to worsening outcomes through nonspecific and specific risks.…
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  • 6 min
  • This content is machine translated Chronic myeloid leukemia

State of the Art – where are we at CML in 2017?

CML patients have a normal life expectancy when treated with Abl-specific kinase inhibitors (TKIs) in chronic phase. Imatinib, dasatinib and nilotinib are approved in the first-line treatment of CML. In…

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