This content is machine translated Monoclonal Gammopathy of Unclear Significance (MGUS) Identification of patients at risk Patients with monoclonal gammopathy of uncertain significance (MGUS) are at increased risk of developing certain forms of cancer. Regular checks allow changes to be detected at an early stage and…
View Post 2 min This content is machine translated Leukemic cutaneous T-cell lymphoma (L-CTCL) Sézary syndrome and mycosis fungoides: STAT5 as a therapeutic target? As the disease progresses, the tumor cells in leukemic variants of cutaneous T-cell lymphomas spread not only in the skin but also in the blood and lymph nodes. Although an…
View Post 6 min This content is machine translated Liquid Biopsy The future of oncological diagnostics With the increasing variety of personalized and immuno-oncological therapeutic options, the importance of predictive markers is also increasing. To date, tissue diagnostics, including invasive biopsy, are necessary to determine this.…
View Post 10 min This content is machine translated Multiple Myeloma A portrait of a multifaceted disease The introduction of new drugs has steadily improved the prognosis of patients with multiple myeloma over the past years. Diagnostics have also been expanded, in particular by cytogenetic analyses, which…
View Post 11 min This content is machine translated Aggressive lymphomas Therapy in everyday clinical practice based on current developments Lymphoma accounts for 3.8% of all new cancer diagnoses. According to the current WHO classification, there are over 75 different lymphomentities, which are treated differently. In the treatment of diffuse… CME-Test
View Post 5 min This content is machine translated Chronic lymphocytic leukemia BTK inhibitors and other hopefuls The therapy of chronic lymphocytic leukemia (CLL) is currently undergoing rapid change. Increasingly, chemoimmunotherapy, which has been commonly used in the past, is being replaced by more targeted treatments. In…
View Post 3 min This content is machine translated Cardio-renal syndrome Iron substitution: when, how and for how long? Iron deficiency in cardio-renal patients is not a trivial matter. Chronic heart failure, for example, is not only a common condition but also often associated with iron deficiency. This in…
View Post 7 min This content is machine translated Non-infectious complications after HSCT Cure for multiple sclerosis at any price? Hematopoietic stem cell transplantation (HSCT) is used as ultima ratio in multiple sclerosis. The reboot of the immune system is aimed at healing, but carries strong side effects. Both infectious…
View Post 5 min This content is machine translated Relapsed/refractory multiple myeloma The BCMA molecule as a beacon of hope The prognosis in relapsed and refractory multiple myeloma (RRMM) remains grim. Now, at the annual meeting of the American Society of Hematology (ASH), data have been presented that raise faint…
View Post 7 min This content is machine translated Non-infectious complications after HSCT Lungs at high risk! Hematopoietic stem cell transplantation (HSCT) is an established treatment for a variety of malignant and non-malignant diseases. However, both infectious and noninfectious pulmonary complications can lead to increased morbidity and…
View Post 10 min This content is machine translated Non-chemotherapy-induced neutropenia Isolated neutropenia: a clinical picture with many faces Neutropenia is a frequent guest in the practice as an independent clinical picture, but also as an accompanying symptom of many diseases and as an adverse drug reaction. The accompanying… CME-Test
