This content is machine translated BRAFV600 stage IV melanoma Targeted therapy: “real world” data on encorafenib plus binimetinib The BERING-Melanoma multicenter study is monitoring the use of encorafenib with binimetinib in the first- and second-line setting* in patients with advanced BRAFV600-mutated malignant melanoma in everyday care in Germany, Austria,…
View Post 2 min This content is machine translated Fixed combination of calcipotriol and betamethasone dipropionate Proactive therapy with spray foam for psoriasis vulgaris persistently effective Proactive management with the foam spray fixed combination of calcipotriol and betamethasone dipropionate resulted in fewer relapses and improved long-term symptom control compared with a reactive treatment strategy with a…
View Post 3 min This content is machine translated Hypercholesterolemia Effective LDL cholesterol reduction with only two injections annually The primary public health goal of WHO is the prevention of atherosclerotic cardiovascular disease. However, a large proportion of patients at high or very high cardiovascular risk do not achieve…
View Post 3 min This content is machine translated Special extract of peppermint and caraway oil Phytopreparation inhibits intestinal motility and promotes secretion An in vitro study on human digestive tissue published in 2021 demonstrated secretion-promoting effects in addition to the muscle-relaxing effects observed in previous studies. In addition, the scientists found that…
View Post 8 min This content is machine translated Mepolizumab as an add-on therapeutic for severe CRSwNP. Symptomatic improvement with good tolerability Approximately 2-4% of the general population is affected by chronic rhinosinusitis with nasal polyps (CRSwNP) [1]. Treatment options were very limited for a long time, but since the approval of…
View Post 6 min This content is machine translated Multiple sclerosis Diroximelfumarate impresses with improved gastrointestinal tolerability [1,2] Diroximel fumarate/DRF is a novel oral fumarate for patients with relapsing-remitting multiple sclerosis (RRMS) that was granted health insurance approval in Switzerland on November 1, 2021, and has been available…
View Post 6 min This content is machine translated Relvar Ellipta improves asthma control [1]. Asthma control is and remains the non-negotiable therapeutic goal Today, fluticasone furoate is the most potent inhaled corticosteroid (ICS) with the highest therapeutic index available to date [2,3]. It is a component of Relvar Ellipta along with vilanterol. Daley-Yates…
View Post 4 min This content is machine translated European Society of Cardiology Annual Congress 2021 Evolocumab provides additional benefit for maximal LDL-C reduction “The lower the better” is an important principle for lipid-lowering therapies, and PCSK9 monoclonal antibodies (PCSK9 mAb), such as evolocumab, can effectively lower LDL-C levels [1]. Data from the ECARA…
View Post 5 min This content is machine translated Immunotherapy Untapped potential in early disease stages Over the last decade, immunotherapy using checkpoint inhibitors has become established in the treatment of many oncological conditions. Especially in advanced tumor disease, ipilimumab, nivolumab and co. play a significant…
View Post 5 min This content is machine translated The metabolic patient Type 2 diabetes: reducing cardiovascular risk through lipid lowering Diabetes is associated with increased cardiovascular risk. Multifactorial therapy of the four major risk factors of blood glucose, weight, hypertension, and dyslipidemia in individuals with type 2 diabetes is challenging.…
View Post 4 min This content is machine translated Atopic dermatitis Long-term efficacy of baricitinib proven In adult patients with moderate to severe atopic dermatitis, long-term therapy with the JAK inhibitor baricitinib maintained improvements achieved after 16 weeks for 68 weeks, new data show. A pooled…
