This content is machine translated Non-small cell lung cancer Who benefits from targeted therapy? A large multicenter study led by the DKFZ-Hector Cancer Institute at the University Medical Center Mannheim confirms substantial differences in treatment response and provides important insights for treatment planning.
View Post 2 min This content is machine translated Cancer Therapy Only individualized nutrition therapy helps prevent malnutrition Low-germ diets in the treatment of cancer patients are associated with significant risks from a scientific perspective and should no longer be practiced.
View Post 9 min This content is machine translated Locally advanced/metastatic breast carcinoma 44th San Antonio Breast Cancer Symposium: Best Of From December 7-10, 2021, the 44th San Antonio Breast Cancer Symposium took place in a physical-virtual hybrid event. In a series of exciting lectures, the latest clinical and preclinical findings…
View Post 6 min This content is machine translated Gliomas New indications for immuno-oncology? While immunotherapies are rapidly gaining ground in other entities, they are still in their infancy in CNS tumors. This is due in part to the often low immunogenicity. Nevertheless, antibody-based therapies,…
View Post 10 min This content is machine translated Iron overload Pathophysiology and clinic Iron overload is an unavoidable and potentially life-threatening consequence of multiple red cell concentrate transfusions. Because the clinical manifestations are nonspecific and usually develop slowly, this complication is often overlooked. CME-Test
View Post 20 min This content is machine translated Head and Neck Tumors New therapies Tumors of the head and neck were the seventh most common cancer worldwide in 2018. The most important risk factors include nicotine and alcohol consumption. The prognosis and multimodality treatment… CME-Test
View Post 3 min This content is machine translated HRD-positive advanced ovarian cancer. PARP inhibitor recommended for first-line maintenance therapy Poly-ADP-ribose polymerase (PARP) inhibitors have added valuable options to the therapeutic landscape in advanced ovarian cancer and have already found their way into ASCO and NCCN guidelines [1–3]. With the…
View Post 12 min This content is machine translated Malignant melanoma Adjuvant Therapy: State of the Art The annual incidence of malignant melanoma has steadily increased over the past 40 years. While the prognosis is good in the early stages, it worsens as the tumor stage increases.… CME-Test
View Post 2 min This content is machine translated Listeria monocytogenes Infectious agent offers protection against liver cancer Liver cancer is the third leading cause of cancer-related deaths worldwide. To date, treatment options for two liver cancers, hepatocellular carcinoma (HCC) and cholangiocarcinoma (CCA), have been inadequate, while new…
View Post 4 min This content is machine translated Pheochromocytomas and paragangliomas Rare neuroendocrine tumors – individualized patient management is essential If a catecholamine-secreting tumor is suspected, determination of metanephrines in free plasma is a sensitive diagnostic method. Paroxysmal hypertension is a common symptom. Depending on the laboratory findings, an imaging…
View Post 4 min This content is machine translated Non-small cell lung cancer Molecular diagnostics under the microscope To date, molecular testing in non-small cell lung cancer (NSCLC) has been reserved primarily for stage IV patients. However, with the introduction of targeted therapies also in earlier tumor stages,…
