This content is machine translated Colorectal cancer screening in ulcerative colitis and Crohn's disease Virtual chromoendoscopy without additional benefit Patients with ulcerative colitis and Crohn’s disease who undergo colonoscopies for surveillance significantly reduce the risk of dying from colorectal cancer. White light videoendoscopy (WLE) is still considered the standard,…
View Post 8 min This content is machine translated Vulvar and vaginal carcinoma Update: precancerous lesions, classification and therapy While vaginal cancer is a rarity, cases of vulvar cancer have increased significantly worldwide over the past 20 years. It is the female carcinoma whose incidence is increasing most rapidly.…
View Post 2 min This content is machine translated Breast Cancer Regulatory extension for anti-PD-1 therapy with pembrolizumab Swissmedic has granted a further marketing authorization for anti-PD-1 therapy with pembrolizumab. This can now be approved in combination with chemotherapy in Switzerland for the treatment of patients with locally…
View Post 2 min This content is machine translated Neoadjuvant treatment with T-VEC Preoperative immunotherapy improves prognosis in metastatic melanoma In a study involving dermatologists from the University Hospital Zurich, preoperative immunotherapy was shown to increase the likelihood of survival and a longer recurrence-free interval in melanoma patients. For patients,…
View Post 9 min This content is machine translated Castleman's disease When is lymph node swelling serious? Periodic, very painful and extensive lymph node swelling may also indicate a rare Castleman’s disease. The rare disease is divided into unicentric Castleman’s disease (UCD) and multicentric forms. The multicentric… CME-Test
View Post 4 min This content is machine translated Non-small cell lung cancer The first targeted therapy for KRAS G12C mutation [1]. After decades of effort, it is now possible for the first time to provide patients with KRAS G12C-mutated non-small cell lung cancer with an effective targeted therapy [1,2]. In the…
View Post 9 min This content is machine translated Hepatocellular carcinoma Systemic treatment of HCC – combination therapies on the rise Hepatocellular carcinoma (HCC) is the most common primary liver cell tumor and presents a challenge in systemic treatment with its intrinsic resistance to classical chemotherapeutic agents. The responsible clinician must… CME-Test
View Post 2 min This content is machine translated Blood-based analytics: clinical application “Liquid biopsy” in malignant melanoma As a biomarker for monitoring the progression of tumor diseases, the detection of tumor cell DNA in blood using next-generation sequencing (“liquid biopsy”) is becoming increasingly important. This also applies…
View Post 4 min This content is machine translated Immuno-oncology Immune checkpoint inhibitors in carcinoma patients – update for the primary care physician. Therapy with anti-PD-1, anti-PDL-1 and anti-CTLA-4 antibodies can also achieve long-term remissions in patients with previously incurable tumor diseases. Whether a carcinoma patient will respond to treatment with checkpoint inhibitors…
View Post 5 min This content is machine translated A portrait of retinoblastoma Double hit cancer With approximately one case per 15,000 to 20,000 live births, retinoblastoma is one of the rare cancers [1]. For those affected – mostly children under the age of three –…
View Post 2 min This content is machine translated Smoking Ban on tobacco advertising to protect children and young people More than a quarter of all Swiss people smoke. Although most people are aware that tobacco use can be associated with major limitations to their health. But quitting smoking is…
