This content is machine translated Pyoderma gangraenosum Extremely painful ulcerations with systemic inflammatory component Pyoderma gangraenosum is an immunologically induced wound, but the exact pathogenesis is not yet clear. The Paracelsus score is an important validated tool for the diagnosis of these extremely painful…
View Post 3 min This content is machine translated Guselkumab in psoriatic arthritis Early response predicted Recent analyses of a heterogeneous group of patients with active psoriatic arthritis (PsA) show that early treatment response with respect to skin psoriasis and enthesitis is a predictor of sustained…
View Post 2 min This content is machine translated Comorbidity Research Depression screening in psoriasis patients. For a cohort study, over 500 adult psoriasis outpatients were screened for depressive symptoms. Despite a low median PASI, the cut-off value for depression was exceeded in almost one in…
View Post 3 min This content is machine translated Management of osteoporosis Reduction of fracture risk through specific osteoporosis medication Osteoporosis leads to an increased risk of fracture due to the loss of bone mass and density. The indication for therapy is mainly based on fracture history, bone density (DXA)…
View Post 5 min This content is machine translated System therapy for psoriasis Targeted treatment with classical and new targets – where is the journey heading? Today, psoriasis is considered an inflammatory systemic disease in which proinflammatory cytokines play an important role. Several inflammatory circuits are involved in the pathogenesis of psoriasis. Cytokines of the IL-23…
View Post 4 min This content is machine translated Psoriatic arthritis therapy Early detection is of high prognostic importance Since psoriatic arthritis often occurs years after the onset of skin psoriasis, dermatologic evaluation of incipient joint involvement is particularly important. Early detection of joint involvement has important therapeutic implications.…
View Post 6 min This content is machine translated Case presentation by Ioannis Papadopoulos, MD. RA patient with severe polyarthritis on JAK inhibitor in remission for more than one year Rheumatoid arthritis (RA) is associated with a high level of suffering for those affected and, if left untreated, can lead to disability. Below, Ioannis Papadopoulos, MD, presents a case in…
View Post 5 min This content is machine translated Psoriasis unguium Therapy of nail psoriasis – an update Patience is needed for the treatment of nail psoriasis. This applies to both local and systemic forms of therapy. Due to the slow growth of the nails, treatment successes only…
View Post 5 min This content is machine translated Systemic sclerosis Therapeutic strategies for a heterogeneous disease. Early detection, risk stratification, and tailored therapy of systemic sclerosis (SSc) are of high importance to counteract disease-related limitations and potentially life-threatening manifestations in a timely manner. Interstitial lung disease…
View Post 3 min This content is machine translated Video interview with two professionals Individualized therapy decisions in osteoporosis The chronic metabolic disease osteoporosis is particularly prevalent among postmenopausal women and can lead to severe health complications [1]. Judith Everts-Graber, MD, and Prof. Serge Ferrari discuss in a video interview…
View Post 9 min This content is machine translated Interview with Prof. Dr. med. Gerd Burmester “With the JAK inhibitors, we can get much more out of them for our patients” Oral Janus kinase inhibitors (JAKi) have been expanding the treatment landscape for inflammatory rheumatoid diseases for several years. In the following interview, Prof. Dr. med. Gerd Burmester explains what this…
