This content is machine translated Multiple sclerosis RAW, PIRA and the disability progression – an overview. Patients with multiple sclerosis acquire disability either through relapse-associated deterioration (RAW) or relapse-independent progression (PIRA). One study now addressed the questions of how early progression begins in the course of…
View Post 5 min This content is machine translated Psoriasis: "Awareness" of comorbidities Cardiometabolic diseases and other comorbidities In addition to certain risk and trigger factors, psoriasis is associated with various comorbidities, such as metabolic syndrome, cardiovascular disease, and depression. This is particularly true for patients with moderate…
View Post 1 min This content is machine translated Podcast JAK inhibitors in inflammatory rheumatic diseases. Thanks to the development of advanced therapies, the goal of remission is within reach for more and more patients with inflammatory rheumatic diseases [1]. In the following podcast, Prof. Stephan…
View Post 7 min This content is machine translated Autoimmune diseases of the skin Therapy of bullous autoimmune dermatoses – an update This article provides an overview of the various forms of bullous autoimmune dermatoses and a summary of current therapeutic recommendations and treatment options. The classical immunosuppressive drugs influence the metabolic… CME-Test
View Post 3 min This content is machine translated Multiple Sclerosis: RRMS Therapy change – strategy for follow-up treatment Until the individually appropriate disease-modifying therapy (DMT) is available, there arein the absence of predictive biomarkers, stepwise optimizations are often necessary, possibly resulting in multiple changes of DMT. To reduce…
View Post 4 min This content is machine translated Pyoderma gangraenosum Extremely painful ulcerations with systemic inflammatory component Pyoderma gangraenosum is an immunologically induced wound, but the exact pathogenesis is not yet clear. The Paracelsus score is an important validated tool for the diagnosis of these extremely painful…
View Post 3 min This content is machine translated Guselkumab in psoriatic arthritis Early response predicted Recent analyses of a heterogeneous group of patients with active psoriatic arthritis (PsA) show that early treatment response with respect to skin psoriasis and enthesitis is a predictor of sustained…
View Post 2 min This content is machine translated Comorbidity Research Depression screening in psoriasis patients. For a cohort study, over 500 adult psoriasis outpatients were screened for depressive symptoms. Despite a low median PASI, the cut-off value for depression was exceeded in almost one in…
View Post 3 min This content is machine translated Management of osteoporosis Reduction of fracture risk through specific osteoporosis medication Osteoporosis leads to an increased risk of fracture due to the loss of bone mass and density. The indication for therapy is mainly based on fracture history, bone density (DXA)…
View Post 5 min This content is machine translated System therapy for psoriasis Targeted treatment with classical and new targets – where is the journey heading? Today, psoriasis is considered an inflammatory systemic disease in which proinflammatory cytokines play an important role. Several inflammatory circuits are involved in the pathogenesis of psoriasis. Cytokines of the IL-23…
View Post 4 min This content is machine translated Psoriatic arthritis therapy Early detection is of high prognostic importance Since psoriatic arthritis often occurs years after the onset of skin psoriasis, dermatologic evaluation of incipient joint involvement is particularly important. Early detection of joint involvement has important therapeutic implications.…