This content is machine translated Paroxysmal nocturnal hemoglobinuria Real-world data on thrombosis predictors and C5 complement inhibitors Paroxysmal nocturnal haemoglobinuria (PNH) is a rare, acquired disease of haematopoietic stem cells of the bone marrow. GPI deficiency results in the absence of complement-regulating proteins. Thromboembolic complications are the...…
View Post 4 min This content is machine translated Paroxysmal nocturnal hemoglobinuria Rare, but well treatable – therefore remember it in practice! Paroxysmal nocturnal hemoglobinuria (PNH) reduces the life expectancy of affected patients and often drastically limits their quality of life. Early diagnosis is extremely important, because today a targeted therapy is…
View Post 8 min This content is machine translated Rituximab, eculizumab, eprodisate New treatment options for glomerular diseases Glomerular diseases are important causes of end-stage renal failure. Pathogenetically, immune-mediated processes are in the foreground. Thanks to advancing knowledge of the pathophysiology and modern genetic engineering methods, there is…
