This content is machine translated Chronic pruritus: itch-scratch circle Hyperreactive intraepidermal nerve fibers Extensive scratching is known to trigger a cascade of mechanisms. An itch-scratch cycle not only impairs the barrier function of the epidermis, but also promotes neuroinflammation in the skin through…
View Post 4 min This content is machine translated Rare skin diseases Porokeratoses – chronic cornification disorder of the epidermis Clinically, porokeratoses are characterized by a keratinization disorder. Several porokeratosis variants are distinguished. A common histologic feature of all porokeratoses is corneal lamellae in the marginal ridge area. Due to…
View Post 6 min This content is machine translated Tyrosine kinase inhibitors and the skin From common to rare side effects Epidermal-growth-factor receptors are found in the skin and sebaceous glands, tyrosine kinase (TK) in keratinizing skin, mucous membranes and hair, and are thus also targets of EGFR- and TK-inhibiting oncologics…
