This content is machine translated Case Report Successful treatment of an acute GPP flare-up Generalized pustular psoriasis (GPP) is a neutrophilic, inflammatory skin disease with a potentially life-threatening course. Recent findings on immunopathogenesis indicate that the group of interleukin (IL)-36 cytokines are central drivers…
View Post 5 min This content is machine translated Pustular psoriasis Current overview of PPP and GPP Pustular forms of psoriasis are relatively rare. An IL-36RN mutation is more common in the generalized subtype (GPP) than in the palmoplantar-restricted subtype (PPP). Both disease entities can occur independently…
View Post 6 min This content is machine translated Generalized Pustular Psoriasis (GPP) What is currently known about this rare systemic disease? Macroscopically visible sterile, confluent pustules on non-acral skin and extensive erythema and edema are among the characteristic manifestations of generalized pustular psoriasis – a severe inflammatory, potentially life-threatening skin disease.…