76-year-old patient with pustular skin rash

The efficacy of spesolimab in the treatment of generalized pustular psoriasis (GPP) is well documented in the literature. In the present case study, spesolimab therapy was administered in parallel with chemotherapy for active metastatic colorectal cancer. After only one infusion, there was a significant improvement in GPP. This case report underlines the safety and efficacy of spesolimab in a patient with active cancer.