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Posts by tag

Second line

7 posts
  • This content is machine translated BRAFV600 stage IV melanoma

Targeted therapy: “real world” data on encorafenib plus binimetinib

The BERING-Melanoma multicenter study is monitoring the use of encorafenib with binimetinib in the first- and second-line setting* in patients with advanced BRAFV600-mutated malignant melanoma in everyday care in Germany, Austria,…
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  • 8 min
  • This content is machine translated Plasma cell myeloma

Preferences in myeloma treatment in Switzerland 2018

With the approval of several new drugs, the treatment spectrum for second-line therapy of plasma cell myeloma has been expanded. In parallel, established treatment concepts, predominantly in first-line treatment, were…
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  • 6 min
  • This content is machine translated DGHO in Vienna

Prostate and breast cancer: the future belongs to combined therapies

Treatment options are often limited in both prostate and breast carcinoma. The search for new effective drugs and combination therapies is therefore the primary goal of current studies.
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  • 4 min
  • This content is machine translated Annual Meeting DGHO, OeGHO, SGMO and SGH+SSH in Stuttgart, Germany

Update hepatocellular carcinoma – news from the system therapy

In hepatocellular carcinoma, an increase in incidence has been observed in industrialized countries. HCC patients have at least two diseases, namely carcinoma as well as severe liver disease. The interaction…
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  • 4 min
  • This content is machine translated PD1/PD-L1 in second-line therapy for metastatic NSCLC.

The agony of choice

The treatment of bronchial carcinoma is greatly changed by immunotherapy. Current developments will lead to an adjustment of our therapy algorithms in the coming months.
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  • 7 min
  • This content is machine translated HER2-positive breast carcinoma

New substances enable targeted therapy

The HER2 receptor belongs to the family of four transmembrane receptor tyrosine kinases (EGFR/HER1, HER2, HER3, and HER4) that influence cell growth, differentiation, and survival. Overexpression of HER2 occurs in…
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  • 4 min
  • This content is machine translated HER2-positive breast cancer and lymphoma

New applications and antibodies

The antibody-drug conjugate trastuzumab emtansine, T-DM1 (Kadcyla®), is composed of the antibody trastuzumab and the chemotherapeutic agent DM1 and is currently being investigated for the treatment of HER2-positive cancers. It…
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