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Allergology and clinical immunology

441 posts
  • This content is machine translated Biologics for atopic dermatitis

Symptom relief through targeted inhibition of inflammatory signaling pathways

Monoclonal antibodies are systems therapeutics that block specific cytokines or receptors and can thus selectively influence individual activation cascades of the immune system. Both dupilumab and tralokinmab – the two…
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  • 3 min
  • This content is machine translated Atopic dermatitis

Multifactorial etiology with dysregulation of type 2 cytokines.

Genetic predisposition, an impaired epidermal barrier with altered microbiome, and aberrant immune responses with type 2 inflammation are associated with the occurrence and activity of atopic dermatitis. Various provoking factors…
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  • 3 min
  • This content is machine translated Chronic cough

Asthma, COPD, or postinfectious?

Anyone who struggles with a respiratory tract infection during the cold season almost always suffers from an unpleasant cough associated with it. This can be quite persistent, but usually disappears…
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  • 3 min
  • This content is machine translated Hymenoptera venom allergy

Summer, sun, insect bite

Hymenoptera venom allergy – commonly called insect venom allergy – is one of the so-called “Big 3” of severe allergic reactions, along with food and drug allergies. No one is…
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  • 6 min
  • This content is machine translated Alopecia areata: drug therapy

Which method achieves the best hair growth rates?

Alopecia areata (AA) manifests as acute or chronic non-scarring hair loss. Diphenylcyclopropenone and Janus kinase inhibitors have a significantly higher remission rate compared with the spontaneous course, especially in severe…
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  • 4 min
  • This content is machine translated Biologics for psoriasis

“Drug Survival” under the microscope

The era of biologics has revolutionized the treatment options for patients with moderate to severe psoriasis in recent decades. Drug survival is an indicator of the longer-term efficacy and safety…
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  • 12 min
  • This content is machine translated Which procedure for which age?

Inhalation with children

Up to 5% of children and adolescents in German-speaking countries live with diseases of the respiratory tract – especially the lungs – and have drug therapy in case of exacerbations,…
CME-Test
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  • 6 min
  • This content is machine translated Early onset asthma

Protect young children from risk factors

About 14% of adolescents worldwide suffer from asthma symptoms. The disease thus represents a significant health burden for children. Exposure to adverse early risk factors may not only influence the…
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  • 4 min
  • This content is machine translated Prurigo nodularis

When excruciating itching proves to be persistent – what helps?

Chronic prurigo is characterized by an “itch-scratch cycle” and is often associated with high levels of distress. The International Forum for the Study of Itch (IFSI) suggests a stage-adapted multimodal…
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  • 7 min
  • This content is machine translated Autoimmune diseases of the skin

Therapy of bullous autoimmune dermatoses – an update

This article provides an overview of the various forms of bullous autoimmune dermatoses and a summary of current therapeutic recommendations and treatment options. The classical immunosuppressive drugs influence the metabolic…
CME-Test
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  • 16 min
  • This content is machine translated Moderate to severe atopic dermatitis

Changing therapeutic landscape – broad arsenal of treatment options

New therapies in the form of specific antibodies and “small molecules” have ushered in a new era. Biologics intervene in the inflammatory process of atopic dermatitis by targeting individual cytokines.…
CME-Test

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