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Allergology and clinical immunology

428 posts
  • This content is machine translated Dupilumab for the treatment of atopic dermatitis

Reduction of Th2-mediated inflammation – therapeutic success also in adolescents

Th2-mediated inflammatory processes play a central pathogenetic role in atopic dermatitis. This is the therapeutic target of the IL4/IL13 inhibitor dupilumab, which was recently approved in Switzerland also for adolescents…
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  • 3 min
  • This content is machine translated Baricitinib

First oral JAK inhibitor approved for the treatment of atopic dermatitis

The use of small molecule drugs for the treatment of atopic dermatitis has been investigated for some time. With the approval of the Janus kinase (JAK) inhibitor baricitinib, a new…
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  • 6 min
  • This content is machine translated Hand eczema

Prevent chronification through early use of topical topical topicals

Hand eczema is associated with psychosocial and socioeconomic follow-up costs. The corona pandemic has significantly increased the prevalence of hand eczema. Affected persons and risk groups should be informed in…
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  • 5 min
  • This content is machine translated Pemphigus diseases

How this autoimmune dermatosis can be managed nowadays

Blistering autoimmune dermatoses of the skin are among the rare diseases and are often fatal if left untreated. Intensive therapy can significantly improve the prognosis and quality of life of…
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  • 6 min
  • This content is machine translated System therapy for atopic dermatitis

What biologics and JAK inhibitors are currently on the research horizon?

The approval of Dupilumab as the first biologic for the treatment of atopic dermatitis represents a significant advance. As a look at ongoing clinical trials shows, research has more arrows…
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  • 4 min
  • This content is machine translated Liver values

Test for viral hepatitis if transaminases are elevated

Altered liver values are not infrequently incidental findings during routine diagnostics. Fatty liver, alcohol abuse, and viral hepatitis are the most common causes of elevated transaminases. Often, several liver diseases…
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  • 1 min
  • This content is machine translated SGAI expert assessment

COVID-19 vaccinations in persons with allergic diseases.

The Swiss Society of Allergology and Immunology (SGAI) has issued recommendations on what to look for in patients with known pre-existing allergic conditions when vaccinating against SARS-CoV-2.
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  • 3 min
  • This content is machine translated BVDD expert assessment

Vaccination against SARS-CoV-2 during immunomodulatory therapy.

What should be considered in patients with chronic inflammatory skin diseases on immunomodulatory or immunosuppressive therapy? The Professional Association of German Dermatologists (BVDD) has published practical recommendations on this subject.
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  • 4 min
  • This content is machine translated Acute generalized exanthematous pustulosis (AGEP).

Not just a T cell-mediated disease?

Immunopathological studies have shown that not only T cells play a role in drug reactions, especially in AGEP, but also IL36 cytokines and other mediators are involved. These findings are…
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  • 9 min
  • This content is machine translated Diaper dermatitis practical

Multifactorial causes, diverse symptoms

Diaper dermatitis is a common condition in infants and incontinent persons, which is directly related to the wearing of a diaper. It heals without complications in most cases. The symptoms…
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  • 2 min
  • This content is machine translated Telemedicine for SLIT

Useful addition – but not a replacement

In the current COVID-19 pandemic, a variety of measures have been taken to minimize the number of direct physician-patient contacts. However, this becomes difficult when using allergen immunotherapy (AIT), the…

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