This content is machine translated Chronic heart failure Recognize early and initiate intervention The incidence and prevalence of chronic heart failure are positively correlated with age, although there are other risk factors such as obesity, diabetes and hypertension. In addition to the treatment…
View Post 4 min This content is machine translated TYK2 inhibition in psoriasis What’s new? The JAK-STAT pathway mediates a variety of proinflammatory responses through Janus kinases (JAK)1-3 andtyrosine kinase-2 (TYK2).Deucravacitinib selectively inhibits TYK2 and was shown to be effective and safe in patients with…
View Post 6 min This content is machine translated Obesity therapy Why lifestyle modification alone is not effective According to current understanding, obesity is considered a multifactorial chronic disease. The overriding goals of treatment are to improve the general state of health and weight-associated diseases or risk factors.…
View Post 8 min This content is machine translated Clinical oncology Innovation meets clinic – treatment approaches for a better outcome The world’s largest and most important congress of clinical oncology took place in Chicago at the beginning of June. The latest data from current studies and innovations in cancer research…
View Post 7 min This content is machine translated Antiretroviral therapy for HIV Holistic management with a view to comorbidities Antiretroviral therapy (ART) has developed enormously over the last 40 years. Data from the “Swiss HIV Cohort Study” show that the life expectancy of HIV patients today hardly differs from…
View Post 4 min This content is machine translated IL-23-i for psoriasis Real-world studies with a focus on PROs Individual therapy goals are playing an increasingly important role in the modern, guideline-oriented treatment of psoriasis. In this context, real-world studies with biologics often not only record the reduction in…
View Post 6 min This content is machine translated Gastrointestinal Cancer Prevention and early detection are becoming increasingly important The treatment of gastrointestinal cancer is catching up with other areas of oncology and offers patients better prospects of survival and quality of life. However, a significant increase in early-onset…
View Post 3 min This content is machine translated IL-17A inhibitors for nail psoriasis 1-year data from the PsoHo study The “Psoriasis Study of Health Outcomes” (PSoHO) is an international, prospective, non-interventional cohort study. In the meantime, new interim analyses have been published of study participants who had nail infestation…
View Post 6 min This content is machine translated Hemophilia A and B Gene therapies show promising results The goals of hemophilia therapy are becoming increasingly ambitious. The aim is now to normalize coagulation as far as possible. For adult patients, gene therapy is now one of many…
View Post 4 min This content is machine translated Joint hypermobility When excessive mobility becomes a problem The 2017 international classification replaces previous terms for symptomatic joint hypermobility. Ehlers-Danlos syndrome (EDS) and hypermobility spectrum disorder (HSD) are clinical diagnoses. The primary therapeutic goals are to alleviate the…
View Post 6 min This content is machine translated Iron Deficiency Anemia Hypochromic microcytic anemia is most common Around 80% of all anemias are iron deficiency anemias. In addition to malnutrition or malabsorption, there may be an increased iron requirement or iron loss due to chronic bleeding. If…
