This content is machine translated Atopic eczema Consistent basic care according to the soak-and-seal principle Regularly administered basic care is an important guideline-based component of treatment, regardless of the severity of atopic dermatitis. In addition to regenerating the disturbed barrier function of the skin, xerosis…
View Post 5 min This content is machine translated Modern lipid management Treating dyslipidemia in diabetes in a target-oriented manner Diabetes is associated with increased cardiovascular morbidity and mortality. Risk-stratified LDL cholesterol lowering is an important component of diabetes therapy and may improve clinical prognosis. In order to achieve the…
View Post 2 min This content is machine translated Chronic nodular prurigo Pruriginous lesional skin exhibits specific DNA methylation signature The question of which mechanisms contribute to the chronification of pruritus in chronic nodular prurigo is the subject of current research. It is hoped that new insights will be gained…
View Post 2 min This content is machine translated Moderate to severe atopic dermatitis “Flares” affect the quality of life Current empirical data underscore the high “burden of disease” in patients with inadequately controlled atopic dermatitis and indicate that there remains a need for highly effective and subgroup-specific systemic therapies.
View Post 4 min This content is machine translated Immuno-oncology Immune checkpoint inhibitors in carcinoma patients – update for the primary care physician. Therapy with anti-PD-1, anti-PDL-1 and anti-CTLA-4 antibodies can also achieve long-term remissions in patients with previously incurable tumor diseases. Whether a carcinoma patient will respond to treatment with checkpoint inhibitors…
View Post 2 min This content is machine translated Parkinson's disease Tracking the variability of phenotypes Whereas earlier disease concepts assumed that patients with PD would follow a rather uniform clinical course within their disease entities (PD, PSP, CBD, MSA), more recent cohort data show that…
View Post 5 min This content is machine translated "Folie à deux" Infections are a frequent trigger of venous thromboembolism Acute infections activate various inflammatory and procoagulant mechanisms and are considered transient risk factors for venous thromboembolism (VTE). Infections not associated with bed rest and hospitalization also increase the risk…
View Post 5 min This content is machine translated "Beyond skin" Tralokinumab: long-term perspectives for patients with atopic dermatitis An excessive Th2 immune response is characteristic of atopic dermatitis. Biologics specifically interfere with signaling cascades of Th2 inflammatory processes. Recently developed novel drugs include tralokinumab. Meanwhile, impressive efficacy evidence from…
View Post 4 min This content is machine translated Schizophrenia Desirable and undesirable effects of antipsychotics. Continuous and effective pharmacotherapy is essential for patients with schizophrenia, as they are at high risk for developing a severe mental illness. But what constitutes successful medication therapy management? This…
View Post 4 min This content is machine translated Chronic inflammatory bowel disease (CED) Vedolizumab in subcutaneous formulation proves its worth in everyday practice That vedolizumab in the maintenance treatment of IBD shows comparable efficacy when administered subcutaneously to intravenous administration has been demonstrated several times. Patients can thus carry out the treatment independently…
View Post 2 min This content is machine translated Obesity Sustainable weight reduction with the help of new therapy options Eat less, move more – obese patients know these recommendations well. However, the implementation is anything but simple. And even if weight loss does occur, the dreaded rebound effect undoes…
