This content is machine translated Psoriatic Arthritis Current GRAPPA recommendations revisited An important message from the Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA) is that patients with psoriatic arthritis (PsA) should be treated on an individualized basis…
View Post 5 min This content is machine translated Nail psoriasis A diagnostic challenge Nail psoriasis is the most common inflammatory dermatosis of the nail apparatus. Most often, but not always, nail infestation occurs together with skin psoriasis. Typical psoriasiform nail changes include spotted…
View Post 4 min This content is machine translated Bullous pemphigoid Updated European expert guideline published The Autoimmune blistering diseases Task Force of the European Academy of Dermatology and Venereology (EADV) recently issued new recommendations for the treatment of bullous pemphigoid. The consensus expert opinion is based…
View Post 3 min This content is machine translated Atopic dermatitis The JAK/STAT pathway as a therapeutic target. Janus kinase (JAK) inhibitors inhibit signal transduction of numerous proinflammatory cytokines with varying selectivity. With baricitinib, upadacitinib and abrocitinib, three oral JAK inhibitors are currently approved in Switzerland for the…
View Post 3 min This content is machine translated Intraepidermal neoplasms Actinic keratosis – a common precancerous condition Actinic keratosis is an intraepidermal neoplasia that can potentially develop into an invasive growing spinocellular carcinoma (SCC). The current study situation does not allow reliable risk stratification. With this in…
View Post 6 min This content is machine translated Rosacea: drug therapy Symptom-oriented treatment strategy – patience pays off In clinical practice, it has become apparent that the previously used subtype classification inadequately reflects the collective of patients with rosacea. This is because different symptoms often overlap and the…
View Post 6 min This content is machine translated Wound Management For wounds that do not heal, also consider rare causes There are very many different and sometimes rare causes of chronic wounds. Correct diagnosis is critical for adequate treatment. A biopsy is often useful for rare and unclear causes. Wound…
View Post 6 min This content is machine translated Inflammatory dermatoses Innovative topical therapy options for atopic dermatitis. Long-term anti-inflammatory treatment options are needed for sustainable management of chronic recurrent atopic eczema. Apart from topically applicable steroids and calcineurin inhibitors, new drug candidates for topical therapy are in…
View Post 4 min This content is machine translated IgE autoreactivity in atopic dermatitis. Study shows association with type 2 comorbidities Atopic dermatitis (AD) is one of the type 2 dominant diseases, caused by complex interactions between genetics and the environment. The role of autoreactive IgE antibodies (auto-IgE) in the pathophysiology of…
View Post 4 min This content is machine translated Psoriasis Tissue-resident memory T cells as “key players”. Immunological memory plays an important role in the pathogenesis of psoriasis. Increasingly, researchers are focusing on tissue resident memory T-cells (TRM cells). This is because the persistence of TRM cells…
View Post 6 min This content is machine translated Chronic urticaria New guideline – Management of urticaria up-to-date At the beginning of 2022, the new urticaria guideline of the German Society for Allergology and Clinical Immunology and the German Dermatological Society was published. Second-generation antihistamines and omalizumab as…
