This content is machine translated New guidelines on plasma cell myeloma Contemporary clarification and therapy The treatment strategy is determined according to the patient’s age and general condition. Younger fit patients receive intensive treatment with induction therapy (at least four cycles), followed by high-dose chemotherapy/autologous…
View Post 7 min This content is machine translated Severe aortic valve stenosis with concomitant mitral regurgitation Does the mitral valve have to be treated as well? Accurate diagnosis lays the foundation in the presence of double valve pathology aortic valve stenosis / mitral valve stenosis. Since the two pathologies influence each other, a multimodality approach including…
View Post 7 min This content is machine translated Post-traumatic stress disorder How can the consequences of traumatization be differentiated? Psychological traumatization can be described as a progressive disease [1] that involves three distinct phases: traumatic situation, traumatic response (up to approximately four weeks after the traumatic event), and traumatic…
View Post 8 min This content is machine translated Surgical techniques and perioperative aspects Current standards of dermatosurgery Dermatosurgery deals with the surgical treatment of mainly malignant, but also benign skin neoplasms. While skin neoplasms were previously often treated by radiotherapy, cryotherapy and electrocautery, new surgical techniques and…
View Post 5 min This content is machine translated Spondylodesis, disc prosthesis and co. - Part 1 Spine surgery for low back pain: what is possible? Chronic low back pain may have a defined pathomorphologic correlate; the main difficulty remains the detection of this correlate. The gold standard of evaluation for back pain is history, clinic,…
View Post 7 min This content is machine translated General allergic reactions Emergency management – anaphylaxis is too rarely recognized The most common triggers of anaphylaxis in adults are drugs and insect bites, and food in children. The development and dynamics of anaphylaxis are unpredictable. According to the WAO recommendation…
View Post 10 min This content is machine translated From high-dose chemotherapy to gene expression. Developments in adjuvant chemotherapy of breast carcinoma. The use of multigene testing is currently limited to the adjuvant setting in HER2-negative luminal breast carcinoma and allows reproducible predictions of recurrence risk. The tests will lead to fewer…
View Post 7 min This content is machine translated Tablets instead of infusions Oral chemotherapy in metastatic breast carcinoma. Oral chemotherapy is an evidence-based option in drug therapy for metastatic breast cancer. Both the favorable side effect profile and the patient autonomy ensured by the oral form of administration…
View Post 4 min This content is machine translated Gain time without delaying therapy Neoadjuvant chemotherapy for breast carcinoma Neoadjuvant chemotherapy is always possible when adjuvant chemotherapy is also indicated. During neoadjuvant chemotherapy, treatment response should be documented so that treatment can be modified if necessary. Neoadjuvant chemotherapy allows…
View Post 8 min This content is machine translated Acute pulmonary embolism The role of surgery Pulmonary embolectomy has become an important therapeutic option in patients with acute massive pulmonary embolism with present signs of right ventricular strain when the indication is carefully and interdisciplinary (cardiac…
View Post 13 min This content is machine translated Mostly harmless, but burdensome Gastrointestinal complaints during pregnancy Nausea, reflux and other functional gastrointestinal symptoms are common in pregnancy and can often be managed with dietary or lifestyle modification. Drug interventions, although safe for mother and child, are…
