This content is machine translated Case reports: Pityriasis rubra pilaris (PRP) Supposedly therapy-resistant PRP responded to biologic treatment The treatment of pityriasis rubra pilaris can be a challenge. The therapeutic arsenal includes topical corticosteroids, phototherapy or classic systemic therapies such as retinoids or immunosuppressants. Recent case reports and…
View Post 3 min This content is machine translated Polyneuropathies Disorders of brain, spinal cord and nerve function Polyneuropathies are generalized diseases of the peripheral nervous system. With a prevalence of 5-8%, patients with chronic alcohol abuse, diabetes or malignant diseases are most affected. In addition to treatment…
View Post 4 min This content is machine translated Rare diseases Niemann-Pick disease Lysosomal storage diseases are a heterogeneous group of genetic disorders that originate from dysfunction of lysosomal metabolic processes. Niemann-Pick disease is nowadays also referred to as ASMD (“Acid Sphingomeyelinase Deficiency”).…
View Post 6 min This content is machine translated Heart Rate Variability - How accurate are smartwatches? Direct comparison with the gold standard in cardiovascular disease A recent study investigated the agreement between heart rate variability derived from the photoplethysmographic signal of a commercially available smartwatch and heart rate variability derived from high-resolution electrocardiogram (gold standard)…
View Post 4 min This content is machine translated Biologics therapy for psoriasis PSoHo cohort study – an interim assessment In clinical trial programs, certain subgroups of patients are excluded based on the respective inclusion criteria. Register studies provide additional data from everyday practice. To date, there have been few…
View Post 8 min This content is machine translated StaRT-CABG Study Intensified statin therapy before coronary artery bypass graft surgery? There is evidence that high-dose statin loading before percutaneous coronary revascularization improves outcomes in patients receiving long-term statins. Therefore, the aim of a recent study was to analyze the effects…
View Post 6 min This content is machine translated Latent hypothyroidism Indication for hormone substitution? In everyday practice, elevated TSH values are usually detected by chance during a routine examination. If the finding is confirmed by a repeat measurement, but the values for free T3…
View Post 8 min This content is machine translated Cardiovascular magnetic resonance Postoperative evaluation of myocardial fibrosis in aortic valve disease. In the chronic course of aortic regurgitation and aortic stenosis, remodeling of the left ventricle occurs, leading to myocardial hypertrophy and fibrosis. Several studies have shown that extracellular volume fraction…
View Post 8 min This content is machine translated "Treat-to-Target" or "High Intensity". Which statin strategy is better? Titrated individually according to LDL target value (“Treat to Target”) or uniformly high doses for all patients (“High Intensity”)? Which of the two strategies is clinically better in the case…
View Post 2 min This content is machine translated Human Biomonitoring First results of pilot phase provides representative data In Switzerland, there are several studies that include human biomonitoring. However, these do not yet provide data representative of Switzerland, so a national study is being considered. Now the first…
View Post 6 min This content is machine translated Moderate depressive disorder Post hoc analysis of a comparative study – Hypericum as an effective antidepressant. Numerous studies show that medicines based on St. John’s wort (Hypericum perforatum) are effective against depressive mood. The evidence base includes not only placebo comparisons, but also reference-controlled comparative studies.…
