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General Internal Medicine

1713 posts
  • This content is machine translated Heart failure

Natural active ingredients such as hawthorn in (preventive) therapy

Heart failure is a complex clinical syndrome that is a leading cause of morbidity and mortality annually in Western industrialized countries. Nutraceuticals have already achieved good clinical results, especially in…
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  • 3 min
  • This content is machine translated GLP-1 receptor agonists in type 2 diabetes

Nephroprotection with semaglutide and liraglutide – direct or indirect effects?

In a post-hoc analysis of large randomized placebo-controlled trials, HbA1c and body weight and blood pressure were examined as mediator variables regarding the renal protective effects of the GLP-1 receptor…
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  • 4 min
  • This content is machine translated Functional gastrointestinal complaints

Visceral hyperalgesia as an important pathomechanism.

Visceral hypersensitivity and motility disorders are thought to be central factors in recurrent gastrointestinal symptoms without evidence of an organ pathologic cause. The gastrointestinal tract is highly innervated and has…
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  • 3 min
  • This content is machine translated From symptom to diagnosis

Lumbar lumbalgia: pseudospondylolisthesis – clinical features of segmental instability.

Pseudospondylolisthesis is a form of spondylolisthesis (slipped vertebra). In most cases, a complex degenerative picture of the segmental structures is seen. Foraminal and spinal stenoses are possible consequences of vertebral…
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  • 1 min
  • This content is machine translated Corona pandemic

EMA reviews first COVID-19 vaccine candidate

AZD1222, a vaccine developed by AstraZeneca in collaboration with the University of Oxford, is under rolling review by the Committee for Medicinal Products for Human Use of the European Medicines…
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  • 5 min
  • This content is machine translated Atrial fibrillation

Stroke prophylaxis by oral anticoagulation

Atrial fibrillation is the most common cardiac arrhythmia and is associated with an increased risk of embolic events. Routine screening facilitates timely detection and treatment. Oral anticoagulants are recommended as…
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  • 3 min
  • This content is machine translated Blood-brain barrier

When breast cancer invades the brain

Patients with breast cancer can develop metastases in the brain – which means an even worse chance of survival. There may be factors in the blood that can predict this…
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  • 4 min
  • This content is machine translated COVID-19

Outpatient care vs. hospitalization: criteria-guided decision support.

A medical expert panel has developed consensus-based criteria as a decision support tool for triage of patients with suspected or confirmed SARS-CoV-2 infection who have only mild symptoms. This is…
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  • 6 min
  • This content is machine translated Anorexia nervosa

The role of the family doctor

Family physicians are often the first point of contact for patients with eating disorders. Targeted screening questions based on the diagnostic criteria can be an aid in recognizing anorectic symptomatology…
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  • 11 min
  • This content is machine translated Sonography in benign liver lesions

Essential imaging procedure for the assessment

Benign liver lesions are common findings on abdominal imaging. In most cases, they cause no symptoms and are discovered by chance. Therefore, it is difficult to provide valid prevalence data.…
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  • 4 min
  • This content is machine translated Diabetic nephropathy

SGLT-2 inhibitor slows decline in glomerular filtration rate

For the first time, a targeted therapy for diabetic kidney disease is available. In the CREDENCE study, canagliflozin resulted in a clinically relevant and statistically significant risk reduction for renal…

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