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General Internal Medicine

1995 posts
  • This content is machine translated Psoriatic arthritis (PsA)

From an interdisciplinary perspective, what are the current “Unmet needs”?

Psoriatic arthritis (PsA) manifests clinically as a heterogeneous disease with phenotypically highly variable expression. Most of those affected already suffer from skin psoriasis. Predicting which psoriasis patients are at increased risk…
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  • 4 min
  • This content is machine translated Infrapatellar pain

M. Osgood-Schlatter – from symptom to diagnosis

The knee joint has a complex structure and is one of the most mechanically stressed joints in humans. In addition to traumatic, inflammatory and degenerative joint damage, septic or aseptic…
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  • 3 min
  • This content is machine translated Acute coronary syndrome

In case of ST-segment elevations in the ECG, immediate revascularization is indicated!

Thoracic pain is a common reason for consultation in the family practice. If an acute coronary syndrome is suspected, the ECG findings, in addition to the clinical presentation and troponin…
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  • 18 min
  • This content is machine translated Overweight and obesity

Diagnostics and therapy for eating disorders

Binge eating disorder is the most common eating disorder in obese people. Early detection and treatment is critical to the progression and prognosis of sustained weight loss. Multimodal combination therapy…
CME-Test
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  • 2 min
  • This content is machine translated RA in over 70s

bDMARDs and JAK inhibitors with lower risk of infection compared to baseline therapy.

In clinical practice, older rheumatoid arthritis patients tend to receive treatment with biologics (bDMARDs) less frequently than younger patients, although the use of conventional basic therapeutics is often not appropriate…
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  • 5 min
  • This content is machine translated State-of-the-Art Obesity Therapy

Combine lifestyle measures with drug treatment

Obesity is on the rise worldwide and is one of the greatest public health challenges of our time. In addition to dietary changes and exercise, GLP-1 agonists are a new…
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  • 4 min
  • This content is machine translated Modern treatment of type 2 diabetes

Combine metformin with new substance classes at an early stage

Lifestyle modification alone is usually not sufficient in type 2 diabetes. Metformin is still considered the first-line drug. However, SGED and international professional societies recommend early combination with an SGLT-2…
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  • 4 min
  • This content is machine translated Axial spondyloarthritis

The road to diagnosis is still far too long

Inflammatory chronic back pain is an indication of possible axial spondyloarthritis. It is a major challenge for primary care physicians to identify those with axSpA among the many back pain…
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  • 11 min
  • This content is machine translated Atopic dermatitis

The role of the key cytokine IL-13

The Th2 response of atopic dermatitis is strongly controlled by IL-13, which activates the type II receptor by binding to the IL-13Rα chain. IL-13 is expressed at higher levels than…
CME-Test
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  • 12 min
  • This content is machine translated Psychotherapy

Conflict management with patients from foreign cultures

A physician’s transcultural understanding of his/her patients from other cultures can help him/her understand, among other things, problems of transcultural marriages, prejudice and its management, illness, and symptoms originating in…
CME-Test
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  • 5 min
  • This content is machine translated Biologics and JAK inhibitors

New insights for RA therapy

There are now four approved JAK inhibitors in Europe: tofacitinib, baricitinib, upadacitinib and filgotinib. While there has not been much news to report on the first two in the past…

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